Tesseroli M A S, Calabrese L, Carvalho A L, Kowalski L P, Chiesa F
Head and Neck Surgery, European Institute of Oncology, Milan, Italy.
Acta Otorhinolaryngol Ital. 2006 Dec;26(6):350-5.
Many Authors have discussed the best indication and extension of neck dissection, but few have studied the surgical approach considering the continuity of neck dissection with the primary tumour. This retrospective study refers to patients submitted to major surgery between 1996 and 2001 for floor of mouth and oral tongue squamous cell carcinoma, at the Head and Neck Surgery Department of the Hospital "A.C. Camargo", São Paulo, Brazil and of the European Institute of Oncology, Milan, Italy. Patients were assigned to one of three groups: group I (in-continuity resection); group 2 (discontinuous resection) and group 3 (delayed discontinuous resection). Overall, 193 patients were studied. There were no differences in disease-free survival between the neck dissection groups. Furthermore, no statistical differences were found in disease specific survival between the groups. Discontinuous neck dissection seems not to change the disease-free survival or disease-specific survival when compared to in-continuity neck dissection, in this retrospective study. A prospective randomized trial is necessary to confirm these results.
许多作者都讨论过颈部清扫术的最佳适应证和范围，但很少有人从颈部清扫术与原发肿瘤的连续性方面研究手术入路。这项回顾性研究涉及1996年至2001年间在巴西圣保罗“A.C. 卡马戈”医院头颈外科以及意大利米兰欧洲肿瘤研究所接受大手术治疗的口底和舌体鳞状细胞癌患者。患者被分为三组之一：第一组（连续切除）；第二组（间断切除）和第三组（延迟间断切除）。总共研究了193例患者。颈部清扫术各组之间的无病生存率没有差异。此外，各组之间的疾病特异性生存率也未发现统计学差异。在这项回顾性研究中，与连续颈部清扫术相比，间断颈部清扫术似乎不会改变无病生存率或疾病特异性生存率。需要进行一项前瞻性随机试验来证实这些结果。
