Methods of evaluating the effect of pharmacological drugs on aging and life span in mice.
作者信息
Anisimov Vladimir N, Popovich Irina G, Zabezhinski Mark A
机构信息
Department of Carcinogenis and Oncogerontology, N.N. Petrov Research Institute of Oncology, St. Petersburg, Russia.
出版信息
Methods Mol Biol. 2007;371:227-36. doi: 10.1007/978-1-59745-361-5_17.
PMID:17634585
Abstract
The methodology of testing anti-aging drugs in laboratory mice is presented. It includes the selection of mouse strain, sex, age at start of treatment, housing conditions, design of the long-term study, some noninvasive methods of assessment, pathology examination, and statistical treatment of the results.
摘要
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