Siassakos D, Wardle P
Department of Obstetrics and Gynaecology, Fertility clinic, Cotswold Centre, Southmead Hospital, North Bristol NHS Trust, Bristol, UK.
BJOG. 2007 Aug;114(8):922-32. doi: 10.1111/j.1471-0528.2007.01418.x.
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women, associated with a characteristic ovarian appearance at ultrasound scan, hyperandrogenism, and ovulatory disorders. The pathogenesis appears to be mainly related to reduced insulin sensitivity in peripheral tissues, leading to hyperinsulinaemia. There is a wide variation in the severity of PCOS symptoms. Women with PCOS are believed to be predisposed to a variety of complications in pregnancy. We present a summary of the evidence surrounding these claims and discuss the weaknesses of the available to date studies.
多囊卵巢综合征（PCOS）是女性最常见的内分泌疾病之一，超声扫描显示具有特征性的卵巢外观，伴有高雄激素血症和排卵障碍。其发病机制似乎主要与外周组织胰岛素敏感性降低有关，进而导致高胰岛素血症。PCOS症状的严重程度差异很大。患有PCOS的女性被认为易在孕期出现各种并发症。我们总结了围绕这些说法的证据，并讨论了迄今为止现有研究的不足之处。
