Second Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece.
Arch Gynecol Obstet. 2010 Sep;282(3):235-9. doi: 10.1007/s00404-010-1495-0. Epub 2010 May 11.
Polycystic ovarian syndrome (PCOS) is a common disease of the endocrine system among the women of reproductive age with an incidence ranging from 5 to 10%.
This study is a mini-review of pregnancy and perinatal outcome in women with PCOS.
The syndrome is associated with increased risk of pregnancy complications such as gestational diabetes, gestational hypertension, preeclampsia, and preterm labor, while no strong association was found with congenital anomalies or spontaneous miscarriages. Furthermore, women with PCOS seem to experience increased risk of cesarean delivery while their newborns face increased perinatal morbidity and mortality. Metformin use seems to reduce the risk of obstetrical complications; however, prospective studies are necessary on the field.
Further studies should be organised in order to evaluate the role of PCOS in pregnancy.
多囊卵巢综合征（PCOS）是一种常见的内分泌系统疾病，在育龄妇女中的发病率为 5%至 10%。
本研究是对多囊卵巢综合征患者妊娠和围产期结局的小型综述。
该综合征与妊娠并发症的风险增加有关，如妊娠期糖尿病、妊娠高血压、子痫前期和早产，而与先天畸形或自然流产无强烈关联。此外，多囊卵巢综合征患者剖宫产的风险似乎增加，而其新生儿的围产期发病率和死亡率增加。二甲双胍的使用似乎降低了产科并发症的风险；然而，该领域仍需要前瞻性研究。
应组织进一步的研究，以评估多囊卵巢综合征在妊娠中的作用。
