Gratz Kim L, Tull Matthew T, Gunderson John G
Center for Addictions, Personality, and Emotion Research and the Department of Psychology, University of Maryland, College Park, MD 20742, USA.
J Psychiatr Res. 2008 Jun;42(7):550-9. doi: 10.1016/j.jpsychires.2007.05.011. Epub 2007 Jul 16.
Although research on the temperamental vulnerabilities associated with borderline personality disorder (BPD) has focused primarily on the role of impulsive-aggression, affective instability, and emotional vulnerability, growing evidence suggests that anxiety sensitivity (AS) also may increase vulnerability for BPD. This study provides preliminary data on the relationship between AS and BPD, examining whether AS distinguishes outpatients with BPD from outpatients without a personality disorder (non-PD), and whether the relationship between AS and BPD is mediated by experiential avoidance (i.e., attempts to avoid unwanted internal experiences, such as anxiety). Findings indicate that BPD outpatients reported higher levels of AS than non-PD outpatients and AS reliably distinguished between these two groups. Furthermore, the relationship between AS and BPD was mediated by experiential avoidance. Finally, results indicate that AS (and experiential avoidance as a mediator) accounted for a significant amount of additional variance in BPD status above and beyond both negative affect and two well-established temperamental vulnerabilities for BPD (affect intensity/reactivity and impulsivity). Findings suggest the need to further explore the role of AS in the pathogenesis of BPD.
尽管关于与边缘型人格障碍(BPD)相关的气质性易感性研究主要集中在冲动攻击性、情感不稳定和情绪易感性的作用上,但越来越多的证据表明,焦虑敏感性(AS)也可能增加患BPD的易感性。本研究提供了关于AS与BPD之间关系的初步数据,考察AS是否能区分BPD门诊患者和无人格障碍(非PD)门诊患者,以及AS与BPD之间的关系是否由经验性回避(即试图避免不必要的内部体验,如焦虑)介导。研究结果表明,BPD门诊患者报告的AS水平高于非PD门诊患者,且AS能可靠地区分这两组患者。此外,AS与BPD之间的关系由经验性回避介导。最后,结果表明,AS(以及作为中介的经验性回避)在BPD状态中解释了超出消极情绪和两种已确立的BPD气质性易感性(情感强度/反应性和冲动性)之外的大量额外变异。研究结果表明有必要进一步探讨AS在BPD发病机制中的作用。