Department of Medicine, University of Queensland, Princess Alexandra Hospital, 4102, Brisbane, Queensland.
Inflammopharmacology. 1998;6(1):1-8. doi: 10.1007/s10787-998-0001-9.
The 'oil' obtained from emu fat can be a very effective inhibitor of chronic inflammation in rats when applied dermally (with a skin penetration enhancer). Assays for this activity using the adjuvant-induced arthritis model have shown: i. Considerable variability in potency of some commercial oil samples; ii. Little or no correlation of activity with colour or linolenic acid (18:3) content of the oil; iii. Relative stability of some active oils (to heat, ageing at room temperature); iv. The bulk of the anti-inflammatory activity was present in a low triglyceride fraction; and v. Potential arthritis-suppressant/immunoregulant activity of these active fractions. These studies point to the need for more rigid quality control before considering such a (now proven) traditional medicine as a complementary therapy.Repeated applications of selected oils did not induce any of the more prominent side-effects associated with NSAIDs (e.g. platelet inhibition, gastrotoxicity) or certain anti-arthritic drugs (proteinuria, leukopenia).
鸸鹋油可作为一种非常有效的抑制剂，抑制慢性炎症在大鼠皮肤表面（与皮肤渗透增强剂一起使用）。用佐剂诱导关节炎模型对该活性进行的检测表明：
i. 一些商业油样的效力有很大的差异；
ii. 活性与油的颜色或亚麻酸（18:3）含量几乎没有相关性；
iii. 一些活性油相对稳定（对热、在室温下老化）；
iv. 大部分抗炎活性存在于低甘油三酯部分；
v. 这些活性部分具有潜在的关节炎抑制/免疫调节活性。
这些研究表明，在考虑将这种（现已证明）传统药物作为补充疗法之前，需要更严格的质量控制。选择的油重复应用不会引起与 NSAIDs（例如血小板抑制、胃毒性）或某些抗关节炎药物（蛋白尿、白细胞减少）相关的更明显的副作用。
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