Hara Kenta, Kajita Ryoko, Torii Keiko U, Bergmann Dominique C, Kakimoto Tatsuo
Department of Biological Science, Graduate School of Sciences, Osaka University, Toyonaka, Osaka 560-0043, Japan.
Genes Dev. 2007 Jul 15;21(14):1720-5. doi: 10.1101/gad.1550707.
Stomata are innovations of land plants that allow regulated gas exchange. Stomatal precursor cells are produced by asymmetric cell division, and once formed, signal their neighbors to inhibit the formation of stomatal precursors in direct contact. We report a gene of Arabidopsis thaliana, EPIDERMAL PATTERNING FACTOR 1 (EPF1) that encodes a small secretory peptide expressed in stomatal cells and precursors and that controls stomatal patterning through regulation of asymmetric cell division. EPF1 activity is dependent on the TOO MANY MOUTHS receptor-like protein and ERECTA family receptor kinases, suggesting that EPF1 may provide a positional cue interpreted by these receptors.
气孔是陆地植物的创新结构，可实现有调控的气体交换。气孔前体细胞通过不对称细胞分裂产生，一旦形成，就会向其相邻细胞发出信号，抑制直接接触的气孔前体的形成。我们报告了拟南芥中的一个基因，表皮模式因子1（EPF1），它编码一种在气孔细胞和前体细胞中表达的小分泌肽，并通过调节不对称细胞分裂来控制气孔模式。EPF1的活性依赖于过多的口受体样蛋白和ERECTA家族受体激酶，这表明EPF1可能提供一种由这些受体解读的位置线索。
