通过脑内接种人乳头多瘤病毒（MMV）产生的仓鼠室管膜瘤。
Hamster ependymomas produced by intracerebral inoculation of a human papovavirus (MMV).
作者信息
Costa J, Yee C, Tralka T S, Rabson A S
出版信息
J Natl Cancer Inst. 1976 Apr;56(4):863-4. doi: 10.1093/jnci/56.4.863.
PMID:176415
Abstract
Ependymomas were produced in 3 of 11 newborn hamsters inoculated intracerebrally with a human papovavirus (MMV) isolated from a malignant lymphoma of the brain of a child with Wiskott-Aldrich syndrome. One of the tumors was serially transplanted into weanling hamsters. Cells from the transplanted tumors and from cell cultures derived from these tumors contained an intranuclear "T" antigen that reacted with simian virus 40 T antibody.
摘要
将从一名患有维斯科特-奥尔德里奇综合征的儿童脑恶性淋巴瘤中分离出的人乳头多瘤病毒（MMV）脑内接种到11只新生仓鼠中，其中3只产生了室管膜瘤。其中一个肿瘤被连续移植到断奶仓鼠体内。移植肿瘤和源自这些肿瘤的细胞培养物中的细胞含有一种与猴病毒40 T抗体发生反应的核内“T”抗原。
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