泰勒氏锥虫血液型的能量代谢
Energy metabolism of bloodstream form Trypanosoma theileri.
作者信息
van Hellemond Jaap J, Hoek Aad, Wichgers Schreur Paul, Chupin Vladimir, Ozdirekcan Suat, Geysen Dirk, van Grinsven Koen W A, Koets Ad P, Van den Bossche Peter, Geerts Stanny, Tielens Aloysius G M
机构信息
Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80176, 3508 TD Utrecht, The Netherlands.
出版信息
Eukaryot Cell. 2007 Sep;6(9):1693-6. doi: 10.1128/EC.00130-07. Epub 2007 Jul 20.
Abstract
Bloodstream form Trypanosoma theileri degrades glucose to acetate (47%) and succinate (45%) and, therefore, does not solely rely on glycolysis for ATP production. This trypanosomatid does not use amino acids for energy metabolism. These results refute the prevailing hypothesis that substrate availability determines the type of energy metabolism of trypanosomatids.
摘要
血液形态的泰勒氏锥虫将葡萄糖降解为乙酸盐（47%）和琥珀酸盐（45%），因此，它并非仅依靠糖酵解来产生ATP。这种锥虫不利用氨基酸进行能量代谢。这些结果驳斥了流行的假说，即底物可用性决定锥虫的能量代谢类型。
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