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315例喉切除术患者的生存分析

[Survival analysis of 315 cases of laryngectomy].

作者信息

Hu Changchen, Wang Binquan, Huangfu Hui, Liu Tao, Xia Lijun, Zhou Liyuan

机构信息

Department of Otorhinolaryngology, First Clinical Hospital of Shanxi Medical University, Taiyuan, 030001, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2007 May;21(10):466-7.

Abstract

OBJECTIVE

To investigation the clinic long-term result and explore the prognostic factor of patients with laryngectomy.

METHOD

Three hundred and fifteen patients with laryngectomy were analysed. The survival rate and the cause of death were collected from this study.

RESULT

Five years later, 233 cases were still alive, 60 cases were dead, 22 cases failed to be followed-up. Overall 5-year survival rate was 73.97%, 5-year survival rate for patients of early stage was 82.69. Whereas, for patients of late stage was 62.64%. Five year survival rate for patients of supraglottic carcinoma, glottic carcinoma, subglottic carcinoma and transglottic carcinoma was respectively 73.76%, 82. 55%, 55.56%, 68.75%. Five year survival rate for patients with partial laryngectomy was 79.89%, whereas, for total laryngectomy was 1.03%. The cause of death were local recurrence and cervical glands metastasis.

CONCLUSION

Early diagnosis was the key points to both larynx preservation and survival rate. for improving survival rate, we should handle the indications strictly. remain sufficient security cutting edge and follow-up visit.

摘要

目的

探讨喉切除患者的临床长期疗效并分析其预后因素。

方法

分析315例喉切除患者,收集本研究中的生存率及死亡原因。

结果

5年后,233例仍存活,60例死亡,22例失访。总体5年生存率为73.97%,早期患者5年生存率为82.69%,晚期患者为62.64%。声门上癌、声门癌、声门下癌及跨声门癌患者的5年生存率分别为73.76%、82.55%、55.56%、68.75%。部分喉切除患者的5年生存率为79.89%,全喉切除患者为1.03%。死亡原因是局部复发和颈部淋巴结转移。

结论

早期诊断是保留喉功能和提高生存率的关键。为提高生存率,应严格掌握手术适应证,保证足够的安全切缘并进行随访。

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