Georgalas C, Babar-Craig H, Arora A, Narula A
Department of Otolaryngology, Head and Neck Surgery, St Mary's Hospital, Paddington, London, UK.
Clin Otolaryngol. 2007 Aug;32(4):268-74. doi: 10.1111/j.1365-2273.2007.01459.x.
To validate the Child Health Questionnaire, measure quality of life in children with obstructive sleep apnoea and assess the impact of surgery.
The primary carer of a consecutive series of 42 patients with sleep disordered breathing referred to a paediatric otolaryngology clinic completed the Child Health Questionnaire (version PF 28). Questionnaires were analysed for data quality and completeness, item/scale correlation, internal consistency and discriminant validity, interscale correlation and reliability. Following overnight pulse oximetry 37 children were diagnosed with obstructive sleep apnoea and underwent adenotonsillectomy.
Child Health Questionnaire Physical Functioning 28 demonstrated excellent measuring characteristics in our population. Compared with normative data, children with obstructive sleep apnoea and their carers suffer a significant quality of life deficit, involving 10 of 13 subscales of the Child Health Questionnaire. This was most prominent in parental emotional impact, general health perception and family activities. There was no correlation between the severity of obstructive sleep apnoea and quality of life indices. Following surgery, there was a significant improvement in all Child Health Questionnaire subscales, which became equivalent to healthy children.
The Child Health Questionnaire Physical Functioning 28 is an accurate and reliable way of assessing the impact of obstructive sleep apnoea on the quality of life in children in Britain. This appears to be significant in most aspects of a child's life, but is fully reversed following surgery.
验证儿童健康问卷，测量阻塞性睡眠呼吸暂停患儿的生活质量，并评估手术的影响。
连续42例转诊至儿科耳鼻喉科门诊的睡眠呼吸障碍患儿的主要照顾者完成了儿童健康问卷（PF 28版）。对问卷进行数据质量和完整性、条目/量表相关性、内部一致性和区分效度、量表间相关性和信度分析。经过夜间脉搏血氧饱和度监测，37名儿童被诊断为阻塞性睡眠呼吸暂停并接受了腺样体扁桃体切除术。
儿童健康问卷身体功能28在我们的研究人群中显示出优异的测量特性。与标准数据相比，阻塞性睡眠呼吸暂停患儿及其照顾者的生活质量存在显著缺陷，涉及儿童健康问卷13个分量表中的10个。这在父母的情绪影响、总体健康感知和家庭活动方面最为突出。阻塞性睡眠呼吸暂停的严重程度与生活质量指标之间没有相关性。手术后，儿童健康问卷的所有分量表都有显著改善，与健康儿童相当。
儿童健康问卷身体功能28是评估阻塞性睡眠呼吸暂停对英国儿童生活质量影响的一种准确可靠的方法。这在儿童生活的大多数方面似乎都很显著，但手术后完全逆转。
