颞叶癫痫精神共病的对照前瞻性研究。
A controlled prospective investigation of psychiatric comorbidity in temporal lobe epilepsy.
作者信息
Jones Jana E, Bell Brian, Fine Jason, Rutecki Paul, Seidenberg Michael, Hermann Bruce
机构信息
Department of Neurology and Biostatistics, University of Wisconsin, Madison, Wisconsin 53792, USA.
出版信息
Epilepsia. 2007 Dec;48(12):2357-60. doi: 10.1111/j.1528-1167.2007.01217.x. Epub 2007 Jul 25.
Temporal lobe epilepsy patients (n = 48) and healthy controls (n = 69) underwent structured psychiatric interview at baseline and 4 years later to characterize the course of DSM-IV Axis I disorders. Adjusting for the influence of prior psychiatric history, epilepsy subjects exhibit significantly greater risk of interval episodes of Total Axis I Disorders and Mood Disorders, indicating a poorer prognosis for these comorbidities in the context of chronic temporal lobe epilepsy.
颞叶癫痫患者（n = 48）和健康对照者（n = 69）在基线时和4年后接受了结构化精神科访谈，以描述DSM-IV轴I障碍的病程。在调整了既往精神病史的影响后，癫痫患者出现轴I障碍和心境障碍发作间期的风险显著更高，这表明在慢性颞叶癫痫的背景下，这些共病的预后较差。
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