Fernando Dinusha, Fowles Jefferson, Woodward Alistair, Christophersen Annemarie, Dickson Stuart, Hosking Matthew, Berezowski Richard, Lea Rod A
Institute of Environmental Science and Research, Wellington, New Zealand.
Tob Control. 2007 Aug;16(4):235-8. doi: 10.1136/tc.2006.018614.
To measure exposure to second-hand smoke (SHS) in New Zealand bars before and after comprehensive smoke-free legislation enacted on 10 December 2004.
Cotinine is the main specific metabolite of nicotine and a well-established biomarker for SHS exposure. We measured cotinine levels in saliva of non-smoking volunteers before and after a 3 h visit to 30 randomly selected bars in 3 cities across the country. Two measures of cotinine before the smoke-free law change during winter and spring 2004, and two follow-up measurements in the same volunteers and venues during winter and spring 2005, were included.
Before the smoke-free law change, in all bars and in all volunteers, exposure to SHS was evident with an average increase in saliva cotinine of 0.66 ng/ml (SE 0.03 ng/ml). Increases in cotinine correlated strongly with the volunteers' subjective observation of ventilation, air quality and counts of lit cigarettes. However, even venues that were judged to be "seemingly smoke free" with "good ventilation" produced discernable levels of SHS exposure. After the law change, there remained some exposure to SHS, but at much lower levels (mean saliva cotinine increase of 0.08 ng/ml, SE 0.01 ng/ml). Smoking indoors in bars was almost totally eliminated: in 2005 only one lit cigarette was observed in 30 visits.
Comprehensive smoke-free legislation in New Zealand seems to have reduced exposure of bar patrons to SHS by about 90%. Residual exposures to SHS in bars do not result from illicit smoking indoors.
测量在2004年12月10日全面无烟立法前后新西兰酒吧内二手烟(SHS)的暴露情况。
可替宁是尼古丁的主要特异性代谢产物,是一种成熟的二手烟暴露生物标志物。我们在全国3个城市随机选择的30家酒吧对非吸烟志愿者进行3小时访问前后,测量了他们唾液中的可替宁水平。纳入了2004年冬春无烟法律变更前的两次可替宁测量,以及2005年冬春在相同志愿者和场所进行的两次随访测量。
在无烟法律变更前,在所有酒吧和所有志愿者中,二手烟暴露明显,唾液可替宁平均增加0.66纳克/毫升(标准误0.03纳克/毫升)。可替宁的增加与志愿者对通风、空气质量和点燃香烟数量的主观观察密切相关。然而,即使是那些被判定为“看似无烟”且“通风良好”的场所,也产生了可察觉的二手烟暴露水平。法律变更后,仍存在一些二手烟暴露,但水平要低得多(唾液可替宁平均增加0.08纳克/毫升,标准误0.01纳克/毫升)。酒吧内的室内吸烟几乎完全消除:2005年在30次访问中仅观察到一支点燃的香烟。
新西兰的全面无烟立法似乎使酒吧顾客的二手烟暴露减少了约90%。酒吧内残留的二手烟暴露并非来自室内非法吸烟。