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高危患者腹腔镜肾脏手术中氦气吹入时的生理变化。

Physiologic changes during helium insufflation in high-risk patients during laparoscopic renal procedures.

作者信息

Makarov Danil V, Kainth Daraspreet, Link Richard E, Kavoussi Louis R

机构信息

The Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

出版信息

Urology. 2007 Jul;70(1):35-7. doi: 10.1016/j.urology.2007.03.010.

DOI:10.1016/j.urology.2007.03.010
PMID:17656203
Abstract

OBJECTIVES

To assess the efficacy and safety of helium as an insufflant for transabdominal laparoscopic renal surgery.

METHODS

The charts of all patients undergoing laparoscopic renal surgery with helium insufflation by a single physician between May 2003 and April 2006 were reviewed. Ventilatory parameters and postoperative recovery were reviewed.

RESULTS

Ten patients underwent laparoscopic renal surgery with helium. These patients had a mean age of 64 years and suffered from a variety of comorbid conditions, including chronic obstructive pulmonary disease (5), congestive heart failure (1), chronic hypoxia from an intrapulmonary shunt (1), malignant hyperthermia (1), and chronic hypoxia from multiple pulmonary infarcts (1). All patients tolerated helium pneumoperitoneum, with mean O2 saturation of 98.6% +/- 0.6%, end-tidal CO2 31.4 +/- 1.7 mm Hg, respiratory rate 9.3 +/- 0.7 breaths per minute, tidal volumes 598.2 +/- 38.0 mL, and peak airway pressures 26.0 +/- 1.2 cm H2O. One patient developed an end-tidal CO2 of greater than 45 mm Hg. Mean operative time was 146.8 +/- 59 minutes, and estimated blood loss was 280.1 +/- 334 mL. Postoperatively 3 patients required continued maintenance of the endotracheal tube, although none required intubation longer than 22 hours. Five patients had critical care monitoring (1.7 +/- 2.9 days on average).

CONCLUSIONS

Helium can be used safely as an insufflant during laparoscopic renal surgery. Patients who may benefit are those with potential difficulty in clearing CO2 gas from their bloodstream or those who rely on sensitive monitoring of end-tidal CO2 to manage comorbid pathology.

摘要

目的

评估氦气作为经腹腹腔镜肾手术气腹剂的有效性和安全性。

方法

回顾了2003年5月至2006年4月间由一名医生采用氦气气腹进行腹腔镜肾手术的所有患者的病历。对通气参数和术后恢复情况进行了评估。

结果

10例患者接受了氦气腹腔镜肾手术。这些患者的平均年龄为64岁,患有多种合并症,包括慢性阻塞性肺疾病(5例)、充血性心力衰竭(1例)、肺内分流导致的慢性缺氧(1例)、恶性高热(1例)以及多发性肺梗死导致的慢性缺氧(1例)。所有患者均耐受氦气气腹,平均氧饱和度为98.6%±0.6%,呼气末二氧化碳分压为31.4±1.7 mmHg,呼吸频率为9.3±0.7次/分钟,潮气量为598.2±38.0 mL,气道峰压为26.0±1.2 cmH₂O。1例患者的呼气末二氧化碳分压超过45 mmHg。平均手术时间为146.8±59分钟,估计失血量为280.1±334 mL。术后3例患者需要继续保留气管插管,尽管无人需要插管超过22小时。5例患者接受了重症监护监测(平均1.7±2.9天)。

结论

氦气可安全地用作腹腔镜肾手术期间的气腹剂。可能受益的患者是那些在从血液中清除二氧化碳气体方面可能存在困难的患者,或者是那些依赖呼气末二氧化碳的敏感监测来管理合并症的患者。

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