Okada M, Ishikawa K, Watanabe K
Faculty of Health and Living Sciences, Naruto University of Education, Tokushima, Japan.
J Nutr Sci Vitaminol (Tokyo). 1991 Aug;37(4):349-57. doi: 10.3177/jnsv.37.349.
The effect of vitamin B6 deficiency was studied on glycogen metabolism in the gastrocnemius muscle, heart, and liver of rats. The glycogen phosphorylase activities in the gastrocnemius muscle and heart but not in the liver of vitamin B6-deficient rats were significantly decreased. The decrease in the enzyme activity in the gastrocnemius muscle was due to decrease in the amount of enzyme. The glycogen content of the muscle of vitamin B6-deficient rats was higher than that of the controls, but the glycogen content of the liver was similar in the two groups. These data suggest that glycogen degradation was impaired in the muscle but not the liver of vitamin B6-deficient rats.
研究了维生素B6缺乏对大鼠腓肠肌、心脏和肝脏糖原代谢的影响。维生素B6缺乏的大鼠腓肠肌和心脏中的糖原磷酸化酶活性显著降低，但肝脏中的活性未降低。腓肠肌中酶活性的降低是由于酶量的减少。维生素B6缺乏的大鼠肌肉中的糖原含量高于对照组，但两组肝脏中的糖原含量相似。这些数据表明，维生素B6缺乏的大鼠肌肉中糖原降解受损，但肝脏中未受损。
