Ko Y C, Lan S J, Yen Y Y, Su I H, Chen B H, Tsai J L
Graduate Institute of Public Health, Kaohsiung Medical College, Taiwan, Republic of China.
Gaoxiong Yi Xue Ke Xue Za Zhi. 1991 Nov;7(11):582-9.
The prevalence of amphetamine use was studied using an anonymous questionnaire given to 3548 adolescent students aged 12--15, with a response rate of 98.6%. This questionnaire was developed and evaluated by the authors. A complete set of data was collected on 3200 subjects, making up 90.2% of all students surveyed. Eighty-five (2.7%) students admitted that they had used amphetamines; that is, 64 of the 1,584 male (4.0%), and 21 of the 1,616 female (1.3%) respondents. The life-time prevalence odds ratio estimation was elevated in male (POR = 3.2, 95% CI 1.9--5.3), as compared to female students. The life-time prevalence rates increased with age only among male students (P trend = 0.01). Seven hundred and twenty four male students were randomly tested for the presence of amphetamines in their urine using thin layer chromatography and fluorescence polarization immunoassay. Of six students who tested positive, five asserted that they had not used amphetamines. The point prevalence rate of amphetamine use based on the urine tests was 0.9% among the 652 students who had completed questionnaires. This rate was higher than on self-reported use of amphetamines (rate difference 0.9%, 95% CI 0.2--1.6%). In this group, 27 (4.1%) admitted that they had used amphetamines. The estimated overall life-time prevalence rate was at least 4.9% (32/652), with 95% CI between 3.2% and 6.6%.
使用一份匿名问卷对3548名12至15岁的青少年学生进行了苯丙胺使用情况的研究，问卷回复率为98.6%。该问卷由作者编制并评估。收集到了3200名受试者的完整数据集，占所有接受调查学生的90.2%。八十五名（2.7%）学生承认他们使用过苯丙胺；也就是说，在1584名男性受访者中有64名（4.0%），在1616名女性受访者中有21名（1.3%）。与女学生相比，男性终身患病率比值比估计值升高（比值比=3.2，95%可信区间1.9 - 5.3）。仅在男学生中，终身患病率随年龄增长而增加（趋势P值=0.01）。使用薄层色谱法和荧光偏振免疫分析法对724名男学生的尿液进行了苯丙胺检测。在检测呈阳性的6名学生中，有5名坚称他们没有使用过苯丙胺。在完成问卷的652名学生中，基于尿液检测的苯丙胺使用点患病率为0.9%。该比率高于自我报告的苯丙胺使用率（率差0.9%，95%可信区间0.2 - 1.6%）。在这组学生中，27名（4.1%）承认他们使用过苯丙胺。估计总体终身患病率至少为4.9%（32/652），95%可信区间在3.2%至6.6%之间。
