Kantovitz Kamila R, Puppin-Rontani Regina M, Gaviao Maria Beatriz D
Department of Pediatric Dentistry, Piracicaba Dental School, State University of Campinas, Brazil.
J Indian Soc Pedod Prev Dent. 2007 Apr-Jun;25(2):69-75. doi: 10.4103/0970-4388.33451.
The purpose was to evaluate two sedation protocols during dental sessions in anxious children.
It was a randomized and double-blind study, with each individual being his/her own control within each protocol. Furthermore, the two protocols were compared. Twenty children (36 to 84 months old) who exhibited "definitely negative" behavior according to the Frankl scale were assigned to receive oral chloral hydrate (40 mg/kg) (Group I) or Diazepam (5 mg) (Group II). Behavior during local anesthesia, application of rubber dam, cavity preparation, restorative procedures was evaluated, considering the degree of sleep, body movement, crying and overall behavior. Vital signs were assessed at three different times. The Wilcoxon, Mann-Whitney, Exact Fisher's and Spearman correlation tests were used to analyze the data.
Group I presented higher scores for sleep during the CH session than placebo session during rubber dam application (P = 0.0431) and restoration (P = 0.0431). In Group II there was no statistically significant difference (p > 0.05). There were no statistically significant differences between sessions and groups in the evaluation of body movement, crying and vital signs. Overall behavior in the placebo session was better than in the CH session during local anesthesia, but there was no difference between the two drug regimens. There was influence of age during anesthesia and cavity preparation in Group I and during rubber dam application in Group II. It was concluded that oral diazepam and chloral hydrate had no influence on the behavior management for dental treatment with the studied sample.
本研究旨在评估两种镇静方案用于焦虑儿童牙科治疗过程中的效果。
这是一项随机双盲研究，每个个体在每种方案中自身作为对照。此外，对两种方案进行比较。选取20名年龄在36至84个月之间、根据弗兰克量表表现出“绝对消极”行为的儿童，分为两组，一组接受口服水合氯醛（40mg/kg）（第一组），另一组接受地西泮（5mg）（第二组）。评估局部麻醉、使用橡皮障、窝洞预备、修复操作过程中的行为，考量睡眠程度、身体活动、哭闹及整体行为情况。在三个不同时间点评估生命体征。采用威尔科克森检验、曼 - 惠特尼检验、精确费舍尔检验和斯皮尔曼相关性检验分析数据。
在使用橡皮障期间及修复过程中，第一组在水合氯醛给药时段的睡眠得分高于安慰剂时段（P = 0.0431）。第二组则无统计学显著差异（p > 0.05）。在身体活动、哭闹及生命体征评估方面，各时段与各分组之间均无统计学显著差异。在局部麻醉期间，安慰剂时段的整体行为优于水合氯醛给药时段，但两种药物方案之间无差异。第一组在麻醉和窝洞预备期间以及第二组在使用橡皮障期间存在年龄影响。研究得出结论，对于本研究样本，口服地西泮和水合氯醛对牙科治疗中的行为管理无影响。
