确定胚胎中的位置信息：超越形态发生素
Specifying positional information in the embryo: looking beyond morphogens.
作者信息
Kerszberg Michel, Wolpert Lewis
机构信息
Université Pierre et Marie Curie-Paris 6, UMR7138 CNRS, 75005 Paris, France.
出版信息
Cell. 2007 Jul 27;130(2):205-9. doi: 10.1016/j.cell.2007.06.038.
PMID:17662932
Abstract
Concentration gradients of small diffusible molecules called morphogens are key regulators of development, specifying position during pattern formation in the embryo. It is now becoming clear that additional or alternative mechanisms involving interactions among cells are also crucial for positional specification.
摘要
被称为形态发生素的可扩散小分子的浓度梯度是发育的关键调节因子，在胚胎模式形成过程中确定位置。现在越来越清楚的是，涉及细胞间相互作用的其他机制或替代机制对于位置指定也至关重要。
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