Malek Marcus M, Emanuel Patrick O, Divino Celia M
Department of Surgery, Mount Sinai School of Medicine, New York, NY 10029, USA.
Dis Colon Rectum. 2007 Sep;50(9):1475-7. doi: 10.1007/s10350-007-0267-9.
This report was designed to discuss the case of a patient taking immunosuppression after transplant who developed squamous-cell carcinoma in a chronic pilonidal cyst and to examine the reported literature on malignant degeneration of pilonidal disease.
We performed a comprehensive literature review and examined the medical record of a patient taking immunosuppressive medications after renal transplant who developed squamous-cell carcinoma in a chronic pilonidal cyst located at the superior gluteal cleft.
Pilonidal disease is a common condition, and it is important to know that malignancy can arise when the disease is chronic. Immunosuppression and human papillomavirus infection may be predisposing factors to malignant degeneration of pilonidal cysts and may accelerate the transformation.
本报告旨在讨论一名移植后接受免疫抑制治疗的患者，其在慢性藏毛囊肿中发生鳞状细胞癌的病例，并查阅已报道的关于藏毛疾病恶性变的文献。
我们进行了全面的文献综述，并查阅了一名肾移植后服用免疫抑制药物的患者的病历，该患者在位于臀上裂的慢性藏毛囊肿中发生了鳞状细胞癌。
藏毛疾病是一种常见病症，重要的是要知道当疾病为慢性时可能会发生恶性变。免疫抑制和人乳头瘤病毒感染可能是藏毛囊肿恶性变的诱发因素，并可能加速这种转变。
