[Prevalence and in vitro antimicrobial susceptibility patterns of Acinetobacter baumannii strains in a Moroccan university hospital].
作者信息
Lahsoune M, Boutayeb H, Zerouali K, Belabbes H, El Mdaghri N
机构信息
Laboratoire de microbiologie, faculté de médecine et de pharmacie, 19, rue Tarik-Bnou-Zyad, Casablanca, Maroc.
出版信息
Med Mal Infect. 2007 Dec;37(12):828-31. doi: 10.1016/j.medmal.2007.05.006. Epub 2007 Jul 31.
OBJECTIVE
The aim of this study was to identify the clinical presentations and the current antimicrobial susceptibility of Acinetobacter baumannii.
RESULTS
We identified 754 strains especially from intensive care units (50.53%) between January 2003 and December 2005. Bronchial swabs and blood culture were prevalent. High-level resistance to betalactamines was noted: 91% to cefotaxime, 50.3% to ceftazidime, and 42.6% to imipenem. Aminoside resistance varied from 17.9% for netilmicine to 72.1% for gentamycin. The resistance rate to ciprofloxacine was 65.8%, and to trimethoprime-sulfamethoxazole 75.8%. In intensive care units, the antimicrobial resistance rate of A. baumannii was higher (p<0.05).
CONCLUSION
The resistance of A. baumannii to current antibiotics is alarming especially in intensive care units. An effective strategy against nosocomial infection is still necessary.
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