Yu Kun, Liu Yinglong, Wang Hongyue, Hu Shengshou, Long Cun
Division of Cardiothoracic Surgery, Extracorporeal Circulation and Anatomic Pathology, Cardiovascular Institute and Fuwai Hospital, CAMS and PUMS, Beijing 100037, China.
Interact Cardiovasc Thorac Surg. 2007 Oct;6(5):636-9. doi: 10.1510/icvts.2007.156554. Epub 2007 Jul 4.
The purpose of this study was to review the current clinical experience and pathological characteristics of cardiac tumors. We retrospectively reviewed 33,108 consecutive cases of cardiac operations performed at our institution from October 1996 to March 2005. There were 242 cases confirmed histologically as cardiac tumors. Among them, 234 patients were diagnosed with primary heart tumors, revealing a prevalence of 0.71% among the corresponding period cardiac operations. Of primary cardiac tumors, the incidence of benign neoplasm was much higher than malignant masses (90.6% vs. 9.4%, P<0.01). The most common benign cardiac tumor was myxoma (86.8%). Mesenchymoma and angiosarcoma were the most common primary malignant cardiac tumors. The prevalence rates of cardiac tumors were quite different among age groups. Rhabdomyoma and fibroma are prone to children. The number of female patients with myxoma was higher than that in male (P<0.01). Myxomas have a special predilection for the left atrium (93.5%). Benign non-myxoma tumors are more likely to occur in the ventricular (64.3%). The primary malignant tumors have a tendency to be of multi-center origination (23%). All the secondary cardiac tumors were located in the right side of the heart. This study, using a relatively large sample, reveals the clinical incidences and pathological characteristics of various cardiac tumors in the Chinese population.
本研究的目的是回顾心脏肿瘤的当前临床经验和病理特征。我们回顾性分析了1996年10月至2005年3月在我院连续进行的33108例心脏手术病例。其中242例经组织学确诊为心脏肿瘤。其中，234例患者被诊断为原发性心脏肿瘤，在同期心脏手术中的患病率为0.71%。在原发性心脏肿瘤中，良性肿瘤的发生率远高于恶性肿瘤（90.6%对9.4%，P<0.01）。最常见的良性心脏肿瘤是黏液瘤（86.8%）。间叶瘤和血管肉瘤是最常见的原发性恶性心脏肿瘤。心脏肿瘤的患病率在不同年龄组中差异很大。横纹肌瘤和纤维瘤易发生于儿童。黏液瘤女性患者数量高于男性（P<0.01）。黏液瘤特别好发于左心房（93.5%）。良性非黏液瘤肿瘤更易发生于心室（64.3%）。原发性恶性肿瘤有多中心起源的倾向（23%）。所有继发性心脏肿瘤均位于心脏右侧。本研究采用相对大的样本，揭示了中国人群中各种心脏肿瘤的临床发病率和病理特征。
