Balleine Bernard W, Delgado Mauricio R, Hikosaka Okihide
Department of Psychology and the Brain Research Institute, University of California Los Angeles, Los Angeles, California 90095-1563, USA.
J Neurosci. 2007 Aug 1;27(31):8161-5. doi: 10.1523/JNEUROSCI.1554-07.2007.
Although the involvement in the striatum in the refinement and control of motor movement has long been recognized, recent description of discrete frontal corticobasal ganglia networks in a range of species has focused attention on the role particularly of the dorsal striatum in executive functions. Current evidence suggests that the dorsal striatum contributes directly to decision-making, especially to action selection and initiation, through the integration of sensorimotor, cognitive, and motivational/emotional information within specific corticostriatal circuits involving discrete regions of striatum. We review key evidence from recent studies in rodent, nonhuman primate, and human subjects.
尽管纹状体参与运动精细调节和控制早已为人所知，但近期对一系列物种中离散的额叶皮质-基底神经节网络的描述，使人们尤其关注背侧纹状体在执行功能中的作用。目前的证据表明，背侧纹状体通过整合涉及纹状体离散区域的特定皮质-纹状体回路中的感觉运动、认知和动机/情感信息，直接参与决策，特别是行动选择和发起。我们回顾了来自啮齿动物、非人类灵长类动物和人类受试者近期研究的关键证据。
