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[苏联首例对人类嗜T淋巴细胞病毒表现出免疫反应的成人T细胞白血病(ATL)]

[The 1st case of adult T-cell leukemia (ATL) with expressed immune response to HTLV in the USSR].

作者信息

Gurtsevich V E, Seniuta N B, Pivnik A V, Pavlish O A, Stepina V N, Syrtsev A V, Iakhnina E I, Kremenetskaia A M

出版信息

Vopr Onkol. 1991;37(5):563-8.

PMID:1767511
Abstract

The first of case of adult T-cell prolymphocytic lymphosarcoma is reported which according to the natural course, cell composition of tumor, cell surface markers as well as expressed immune response to a wide spectrum of HTLV-1 gag an env encoded proteins can be classified as HTLV-associated adult T-cell leukemia. Diagnosis of the tumor alongside with identification of HTLV-1-infected individuals in the USSR emphasizes the need to stimulate research in HTLV-1-associated carcinogenesis in this country.

摘要

首例成人T细胞原淋巴细胞性淋巴肉瘤病例被报道,根据其自然病程、肿瘤细胞组成、细胞表面标志物以及对多种HTLV-1 gag和env编码蛋白表达的免疫反应,该病例可归类为HTLV相关成人T细胞白血病。该肿瘤的诊断以及苏联境内HTLV-1感染个体的识别强调了在该国推动HTLV-1相关致癌作用研究的必要性。

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