Ando Takao, Yasui Jun-Ichi, Inokuchi Naoko, Usa Toshiro, Ashizawa Kiyohito, Kamihara Shimeru, Eguchi Katsumi
First Department of Medicine, Nagasaki University of Medicine.
Intern Med. 2007;46(15):1225-9. doi: 10.2169/internalmedicine.46.0188. Epub 2007 Aug 2.
Clinical assays are very important for the diagnosis and management of clinical disorders. Each assay system consists of a specific method to detect and/or quantify a substance of interest in the clinical specimen. However, clinical assays can be unfavorably influenced by non-specific activities concomitantly present in the specimen, which may mislead clinical decisions. Thus, it is very important to know how each assay works, and how and when the assay is non-specifically influenced. Here, we report three cases shown clinical data of thyroid function influenced by new type of assay interference.
临床检测对于临床疾病的诊断和管理非常重要。每个检测系统都由一种特定的方法组成，用于检测和/或定量临床标本中感兴趣的物质。然而，临床检测可能会受到标本中同时存在的非特异性活性的不利影响，这可能会误导临床决策。因此，了解每个检测如何工作，以及该检测如何以及何时受到非特异性影响非常重要。在此，我们报告三例显示新型检测干扰影响甲状腺功能临床数据的病例。
