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尼古丁透皮贴剂联合认知行为疗法的十年生存结局

Ten-year survival outcome of the nicotine transdermal patch with cognitive behavioural therapy.

作者信息

Richmond Robyn L, Kehoe Linda

机构信息

School of Public Health and Community Medicine, University of New South Wales, Kensington, New South Wales 2052.

出版信息

Aust N Z J Public Health. 2007 Jun;31(3):282-5. doi: 10.1111/j.1467-842x.2007.00062.x.

Abstract

OBJECTIVE

To follow-up abstainers from the end of their initial treatment over seven points to 10 years.

METHODS

In the original study there were 305 smokers who were recruited in a double-blind randomised controlled trial. Those subjects who had remained continuously abstinent to seven years (n=20) were followed up to ascertain continuous smoking prevalence to 10 years. Main outcome measure was continuous abstinence.

RESULTS

At 10 years, the active nicotine patch group showed significantly higher continuous abstinence rates that were double those of the placebo group (7.9% vs. 2.6%, respectively). The high rate of relapse declined after six months.

CONCLUSIONS

The nicotine patch leads to superior continuous abstinence over 10 years when compared with placebo. PUBLIC HEALTH IMPLICATIONS: This is the longest follow-up study of continuous smoking abstinence after cognitive behaviour treatment combined with the nicotine patch.

摘要

目的

对最初治疗结束后七年至十年的戒烟者进行随访。

方法

在原研究中,305名吸烟者被纳入一项双盲随机对照试验。对持续戒烟七年的受试者(n = 20)进行随访,以确定到十年时的持续吸烟率。主要结局指标为持续戒烟。

结果

在十年时,活性尼古丁贴片组的持续戒烟率显著更高,是安慰剂组的两倍(分别为7.9%和2.6%)。六个月后复发率较高的情况有所下降。

结论

与安慰剂相比,尼古丁贴片在十年期间能带来更优的持续戒烟效果。公共卫生意义:这是认知行为治疗联合尼古丁贴片后持续戒烟的最长随访研究。

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