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日本普通人群中高血压患者中肥胖所致高血压患者的比例:日本国家数据库80、90。

The proportion of individuals with obesity-induced hypertension among total hypertensives in a general Japanese population: NIPPON DATA80, 90.

作者信息

Nakamura Koshi, Okamura Tomonori, Hayakawa Takehito, Hozawa Atsushi, Kadowaki Takashi, Murakami Yoshitaka, Kita Yoshikuni, Okayama Akira, Ueshima Hirotsugu

机构信息

Department of Health Science, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu City, Shiga, 520-2192, Japan.

出版信息

Eur J Epidemiol. 2007;22(10):691-8. doi: 10.1007/s10654-007-9168-4. Epub 2007 Aug 7.

Abstract

The increased prevalence of obesity in Japan may contribute to the high prevalence of hypertension in Japan. In the present study, we calculated the odds ratio for hypertension in obesity (body mass index (BMI) >or= 25.0 kg/m(2)) using data from independent nationwide surveys conducted in 1980 and 1990. We estimated the percentage of hypertensives whose condition was due to obesity among total hypertensives in the general Japanese population. In the 1980 survey, 18.8% of 4,623 male participants were obese and 50.4% were hypertensive, whereas 22.6% of 5,893 female participants were obese and 41.1% were hypertensive. For both sexes, obese participants had a higher odds ratio for hypertension than non-obese participants (BMI < 25.0 kg/m(2)), and there was a significant dose-response relationship between BMI and the odds ratio for hypertension. Among all hypertensives, the percentage whose hypertension was due to obesity in 1980 and 1990 was 11.4% (95% confidence interval (CI): 4.7-17.7%) and 15.3% (95% CI: 6.8-23.1%) for men and 19.3% (95% CI: 12.1-25.9%) and 22.3% (95% CI: 14.6-29.3%) for women, respectively. Approximately 80-90% of individuals with obesity-induced hypertension were in the 25.0 <or= BMI < 30.0 kg/m(2) category for both sexes in each year. In conclusion, we found that obesity-induced hypertension as a proportion of total hypertension increased between 1980 and 1990 for both sexes. Obesity now is playing a more important role in the high prevalence of hypertension in Japan than it was before.

摘要

日本肥胖症患病率的上升可能是导致该国高血压高患病率的原因之一。在本研究中,我们利用1980年和1990年独立进行的全国性调查数据,计算了肥胖(体重指数(BMI)≥25.0 kg/m²)人群患高血压的比值比。我们估算了日本普通人群中因肥胖导致高血压的患者在所有高血压患者中所占的百分比。在1980年的调查中,4623名男性参与者中有18.8%肥胖,50.4%患有高血压;而5893名女性参与者中有22.6%肥胖,41.1%患有高血压。无论男女,肥胖参与者患高血压的比值比均高于非肥胖参与者(BMI<25.0 kg/m²),且BMI与高血压比值比之间存在显著的剂量反应关系。在所有高血压患者中,1980年和1990年因肥胖导致高血压的男性患者比例分别为11.4%(95%置信区间(CI):4.7 - 17.7%)和15.3%(95% CI:6.8 - 23.1%),女性患者比例分别为19.3%(95% CI:12.1 - 25.9%)和22.3%(95% CI:14.6 - 29.3%)。每年,约80 - 90%的肥胖所致高血压患者的BMI处于25.0≤BMI<30.0 kg/m²范围。总之,我们发现1980年至1990年期间,男女因肥胖导致的高血压在总高血压病例中所占比例均有所增加。如今,肥胖在日本高血压高患病率中所起的作用比以往更为重要。

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