Parfitt H S, Davies S V, Tighe P, Ewings P
Musgrove Park Hospital, Taunton, Somerset, UK.
Transfus Med. 2007 Aug;17(4):290-5. doi: 10.1111/j.1365-3148.2007.00774.x.
The aim of this study was to assess the performance in terms of red cell damage of two peristaltic volumetric infusion pumps - the Alaris IVAC 572 (San Diego, CA, USA) and Arcomed Volumed VP7000 (Regensdorf, Switzerland). Various infusion pumps are available to transfuse blood at a predetermined rate. It is recommended that each machine should be individually assessed. This experiment used six units of single-donor-transfusable packed red cells and ran each unit through both pumps. This was carried out at 9, 28 and 35 days post-donation at rates from 2 to 150 mL h(-1). Post-pumping samples from these experiments, and a pre-pumping sample in each case, were analysed for levels of potassium and free haemoglobin (Hb). They were also examined microscopically for evidence of cell damage. Potassium levels showed no significant change with pumping on any occasion, but rose significantly as the samples aged. Free Hb showed some variation, but the only consistent finding was a similar rise in value with increasing pack age. Microscopic examination revealed no cell damage under any condition. Both pumps performed to an acceptable level and appear safe to be used for red cell transfusion.
本研究的目的是评估两款蠕动式容积输液泵——美国加利福尼亚州圣地亚哥的阿拉瑞斯IVAC 572和瑞士雷根斯多夫的阿科美德Volumed VP7000在红细胞损伤方面的性能。有多种输液泵可用于以预定速率输血。建议对每台机器进行单独评估。本实验使用了六个单位的单供体可输血浓缩红细胞，并让每个单位通过两台泵运行。这是在采血后第9天、28天和35天以2至150 mL h⁻¹的速率进行的。对这些实验的泵后样本以及每种情况下的泵前样本进行了钾和游离血红蛋白（Hb）水平分析。还对它们进行了显微镜检查以寻找细胞损伤的证据。钾水平在任何情况下泵血后均无显著变化，但随着样本老化而显著升高。游离Hb有一些变化，但唯一一致的发现是其值随血袋保存时间增加而类似地升高。显微镜检查显示在任何条件下均无细胞损伤。两台泵的性能均达到可接受水平，似乎可安全用于红细胞输血。
