• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

系统性红斑狼疮中的闭塞性细支气管炎:静脉注射环磷酰胺的有益作用。

Bronchiolitis obliterans in systemic lupus erythematosus: beneficial effect of intravenous cyclophosphamide.

作者信息

Godeau B, Cormier C, Menkes C J

机构信息

Department of Rheumatology, Cochin Hospital, Paris, France.

出版信息

Ann Rheum Dis. 1991 Dec;50(12):956-8. doi: 10.1136/ard.50.12.956.

DOI:10.1136/ard.50.12.956
PMID:1768170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1004592/
Abstract

A 49 year old white woman with systemic lupus erythematosus and bronchiolitis obliterans was treated with prednisone (1 mg/kg daily), which led to a transitory improvement in pulmonary status. Cyclophosphamide was then added--4 mg/kg daily intravenously for five days, then 2 mg/kg daily orally--and this was followed by a dramatic and prolonged improvement.

摘要

一名49岁患有系统性红斑狼疮和闭塞性细支气管炎的白人女性接受了泼尼松治疗(每日1毫克/千克),这使肺部状况得到了短暂改善。随后添加了环磷酰胺——静脉注射每日4毫克/千克,持续五天,然后改为口服每日2毫克/千克——之后病情出现了显著且持久的改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144b/1004592/c22a65c5463f/annrheumd00461-0063-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144b/1004592/8fa4303f8fc5/annrheumd00461-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144b/1004592/c22a65c5463f/annrheumd00461-0063-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144b/1004592/8fa4303f8fc5/annrheumd00461-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144b/1004592/c22a65c5463f/annrheumd00461-0063-a.jpg

相似文献

1
Bronchiolitis obliterans in systemic lupus erythematosus: beneficial effect of intravenous cyclophosphamide.系统性红斑狼疮中的闭塞性细支气管炎:静脉注射环磷酰胺的有益作用。
Ann Rheum Dis. 1991 Dec;50(12):956-8. doi: 10.1136/ard.50.12.956.
2
[Lupus bronchiolitis obliterans: diagnostic difficulties].[闭塞性细支气管炎型狼疮:诊断困难]
Rev Med Interne. 1994 May;15(5):332-5. doi: 10.1016/s0248-8663(05)81440-7.
3
Cyclophosphamide therapy is effective for bronchiolitis obliterans occurring as a late manifestation of lupus erythematosus.
Br J Dermatol. 2000 Aug;143(2):453-5. doi: 10.1046/j.1365-2133.2000.03685.x.
4
Bronchiolitis obliterans in systemic lupus erythematosus.系统性红斑狼疮中的闭塞性细支气管炎
Ann Rheum Dis. 1992 Jul;51(7):927. doi: 10.1136/ard.51.7.927-b.
5
Cyclophosphamide in treatment of systemic lupus erythematosus: 7 years' experience.环磷酰胺治疗系统性红斑狼疮:7年经验
Br Med J. 1973 May 26;2(5864):450-2. doi: 10.1136/bmj.2.5864.450.
6
The association of bronchiolitis obliterans organizing pneumonia, systemic lupus erythematosus, and Hunner's cystitis.闭塞性细支气管炎机化性肺炎、系统性红斑狼疮与Hunner膀胱炎的关联
Chest. 1993 Aug;104(2):642-4. doi: 10.1378/chest.104.2.642.
7
Transverse myelitis in systemic lupus erythematosus--the effect of IV pulse methylprednisolone and cyclophosphamide.系统性红斑狼疮所致横贯性脊髓炎——静脉注射甲泼尼龙冲击疗法和环磷酰胺的疗效
J Rheumatol. 1992 Mar;19(3):370-2.
8
Monthly intravenous cyclophosphamide in the treatment of severe systemic lupus erythematosus.每月静脉注射环磷酰胺治疗重症系统性红斑狼疮。
Clin Exp Rheumatol. 1984 Jul-Sep;2(3):247-51.
9
Intravenous cyclophosphamide pulse therapy in the treatment of systemic lupus erythematosus. Long-term results.
Contrib Nephrol. 1992;99:126-8. doi: 10.1159/000421702.
10
Severe airflow limitation in two patients with systemic lupus erythematosus: effect of inhalation of anticholinergics.两名系统性红斑狼疮患者的严重气流受限:吸入抗胆碱能药物的效果
Mod Rheumatol. 2008;18(1):52-6. doi: 10.1007/s10165-007-0002-3. Epub 2007 Dec 20.

引用本文的文献

1
Bronchiolar disorders in systemic autoimmune rheumatic diseases.系统性自身免疫性风湿疾病中的细支气管疾病
Eur Respir Rev. 2025 Apr 16;34(176). doi: 10.1183/16000617.0248-2024. Print 2025 Apr.
2
Bronchiolitis obliterans organizing pneumonia in patients with autoimmune rheumatic diseases.自身免疫性风湿疾病患者的机化性细支气管炎伴机化性肺炎
Immunol Res. 2015 Feb;61(1-2):97-103. doi: 10.1007/s12026-014-8607-z.
3
Pleuropulmonary manifestations of systemic lupus erythematosus.系统性红斑狼疮的胸膜肺部表现

本文引用的文献

1
[Severe bronchiolitis in 3 cases of rheumatoid polyarthritis treated with D-penicillamine].[3例类风湿性多关节炎患者使用青霉胺治疗后发生严重细支气管炎]
Rev Fr Mal Respir. 1981;9(2):147-9.
2
Pulmonary function abnormalities in systemic lupus erythematosus responsive to glucocorticoid therapy.系统性红斑狼疮患者中对糖皮质激素治疗有反应的肺功能异常。
Chest. 1981 Jun;79(6):702-4. doi: 10.1378/chest.79.6.702.
3
Bronchiolitis in systemic lupus erythematosus.系统性红斑狼疮中的细支气管炎
Thorax. 2000 Feb;55(2):159-66. doi: 10.1136/thorax.55.2.159.
4
Bronchiolitis obliterans in systemic lupus erythematosus.系统性红斑狼疮中的闭塞性细支气管炎
Ann Rheum Dis. 1992 Jul;51(7):927. doi: 10.1136/ard.51.7.927-b.
Chest. 1982 Nov;82(5):646-9. doi: 10.1378/chest.82.5.646.
4
The spectrum of bronchiolitis obliterans.闭塞性细支气管炎的谱系
Chest. 1983 Feb;83(2):161-2. doi: 10.1378/chest.83.2.161.
5
Beneficial effect of intravenous cyclophosphamide and oral prednisone on D-penicillamine-associated bronchiolitis obliterans.
Arthritis Rheum. 1985 Jan;28(1):93-7. doi: 10.1002/art.1780280115.
6
Bronchiolitis obliterans organizing pneumonia.闭塞性细支气管炎伴机化性肺炎
N Engl J Med. 1985 Jan 17;312(3):152-8. doi: 10.1056/NEJM198501173120304.
7
Bronchiolitis obliterans and usual interstitial pneumonia. A comparative clinicopathologic study.闭塞性细支气管炎与普通间质性肺炎。一项比较临床病理研究。
Am J Surg Pathol. 1986 Jun;10(6):373-81. doi: 10.1097/00000478-198606000-00002.
8
Pulmonary function of nonsmoking patients with systemic lupus erythematosus.系统性红斑狼疮非吸烟患者的肺功能
Chest. 1988 Aug;94(2):312-5. doi: 10.1378/chest.94.2.312.
9
The pulmonary manifestations of systemic lupus erythematosus.系统性红斑狼疮的肺部表现。
Semin Arthritis Rheum. 1985 Feb;14(3):202-24. doi: 10.1016/0049-0172(85)90040-x.
10
Airways obstruction in a case of disseminated lupus erythematosus.一例播散性红斑狼疮患者的气道阻塞
Thorax. 1978 Dec;33(6):814-5. doi: 10.1136/thx.33.6.814.