Godeau B, Cormier C, Menkes C J
Department of Rheumatology, Cochin Hospital, Paris, France.
Ann Rheum Dis. 1991 Dec;50(12):956-8. doi: 10.1136/ard.50.12.956.
A 49 year old white woman with systemic lupus erythematosus and bronchiolitis obliterans was treated with prednisone (1 mg/kg daily), which led to a transitory improvement in pulmonary status. Cyclophosphamide was then added--4 mg/kg daily intravenously for five days, then 2 mg/kg daily orally--and this was followed by a dramatic and prolonged improvement.
一名49岁患有系统性红斑狼疮和闭塞性细支气管炎的白人女性接受了泼尼松治疗(每日1毫克/千克),这使肺部状况得到了短暂改善。随后添加了环磷酰胺——静脉注射每日4毫克/千克,持续五天,然后改为口服每日2毫克/千克——之后病情出现了显著且持久的改善。