Martinez Kennedy de Oliveira, Mendes Lauro Lúcio, Alves José Bento
Morphologic Sciences, University of Uberaba.
Braz J Otorhinolaryngol. 2007 May-Jun;73(3):323-8. doi: 10.1016/s1808-8694(15)30075-6.
Clinical and experimental study. Introduction. Of debatable etiology, Recurrent Aphthous Ulcerations (R.A.U), is most of the time considered an immunological deficiency.
The aim of this paper is to review the literature and clinical investigations regarding IgA-s, total proteins salivary concentration and basal salivary flow of patients with R.A.U. during activity and quiescence.
Nephelometry was used to measure salivary IgA-s; Pyrogallol red was used for total salivary proteins and the gravimetrical analysis for salivary flow measurement.
Results demonstrated a significant increase in salivary IgA-s in active lesions in relation to quiescence. On the other hand, protein concentration rates were similar in both periods.
Salivary IgA-s can be used as a parameter to study the immune status of the oral mucosa.
临床与实验研究。引言。复发性阿弗他溃疡(R.A.U)病因存在争议,多数情况下被认为是一种免疫缺陷。
本文旨在回顾关于R.A.U患者在活动期和静止期唾液中IgA、总蛋白浓度及基础唾液流量的文献和临床研究。
采用比浊法测量唾液IgA;焦性没食子酸红用于检测唾液总蛋白,重量分析法用于测量唾液流量。
结果表明,与静止期相比,活动期病变唾液中IgA显著增加。另一方面,两个时期的蛋白质浓度率相似。
唾液IgA可作为研究口腔黏膜免疫状态的一个参数。