将普鲁士蓝纳米颗粒固定在硫醇自组装单分子层修饰的金电极上用于电分析或生物传感器应用。
Immobilization of Prussian Blue nanoparticles onto thiol SAM modified Au electrodes for electroanalytical or biosensor applications.
作者信息
Miao Yuqing, Chen Jianrong, Wu Xiaohua, Fang Keming, Jia Aiping, Liu Jiwei
机构信息
Zhejiang Key Laboratory for Reactive Chemistry on Solid Surfaces, Institute of Physical Chemistry, Zhejiang Normal University, Jinhua 321004, China.
出版信息
J Nanosci Nanotechnol. 2007 Aug;7(8):2877-82. doi: 10.1166/jnn.2007.672.
Poly(vinylpyrrolidone) (PVP)-protected Prussian Blue (PB) nanoparticles were prepared by simply mixing FeCI3 and K4Fe(CN)6 with absence or presence of HCI or/and KCI in water solution. The obtained PB nanoparticles were immobilized onto thiol self-assembled monolayer (SAM) modified Au electrodes. L-cysteine (Cys) and 1,8-octanedithiol (ODT) were compared as a bridge between the gold surface and the PB nanoparticles. The results show that PB prepared from the initial solution with KCI gives preferred electrochemical response and that Cys/Au shows improved immobilization effect of PB than ODT/Au. The obtained PB/Cys/Au electrodes exhibit electrocatalytic activity toward H2O2 reduction and DL-homocysteine (HCys) oxidation. Glucose oxidase (GOX) was immobilized onto PB modified electrode to explore the potentials for the design of oxidase-based biosensors. It is possible to anchor PB nanoparticles and develop their application on electroanalysis and biosensing.
通过在水溶液中在有无HCl或/和KCl的情况下简单混合FeCl3和K4Fe(CN)6制备了聚乙烯吡咯烷酮（PVP）保护的普鲁士蓝（PB）纳米颗粒。将得到的PB纳米颗粒固定在硫醇自组装单层（SAM）修饰的金电极上。比较了L-半胱氨酸（Cys）和1,8-辛二硫醇（ODT）作为金表面和PB纳米颗粒之间的桥梁。结果表明，由含KCl的初始溶液制备的PB具有较好的电化学响应，并且Cys/Au对PB的固定效果优于ODT/Au。所制备的PB/Cys/Au电极对H2O2还原和DL-高半胱氨酸（HCys）氧化表现出电催化活性。将葡萄糖氧化酶（GOX）固定在PB修饰电极上，以探索基于氧化酶的生物传感器的设计潜力。固定PB纳米颗粒并开发其在电分析和生物传感中的应用是可能的。
Zotero 插件