Entwistle M D, Roe P G, Sapsford D J, Berrisford R G, Jones J G
Department of Anaesthetics, Bradford Royal Infirmary.
Br J Anaesth. 1991 Dec;67(6):704-11. doi: 10.1093/bja/67.6.704.
We have studied patterns of oxygen saturation (SpO2) before and after thoracotomy in 20 patients monitored nightly from the preoperative night to the fourth postoperative night. After operation, 10 patients received paravertebral bupivacaine (PVB) infusion and 10 received paravertebral saline (PVS) infusion. Papaveretum was given as required. Before operation the SpO2 profiles formed two groups: stable with SpO2 greater than 94% and stable with a median SpO2 less than 94% (hypoxaemia). During the first night after operation SpO2 profiles formed four groups: stable, not hypoxaemic (2/20); stable, hypoxaemic but improving (8/20); stable and constant hypoxaemia (5/20); unstable, hypoxaemic and deteriorating (5/20). Eleven patients remained hypoxaemic as late as the fourth night after operation. All patients who were hypoxaemic before operation were hypoxaemic after operation. Postoperative hypoxaemia was predicted in only 50% of cases. Papaveretum requirement was reduced in the PVB group, but regional analgesia did not affect the proportion of patients showing each SpO2 profile. Papaveretum caused a decrease in SpO2 in both analgesic groups.
我们研究了20例患者开胸手术前后的血氧饱和度(SpO2)模式,从术前一晚至术后第四晚每晚进行监测。术后,10例患者接受椎旁布比卡因(PVB)输注,10例接受椎旁生理盐水(PVS)输注。按需给予吗啡。术前SpO2模式形成两组:SpO2大于94%且稳定,以及SpO2中位数小于94%(低氧血症)且稳定。术后第一晚,SpO2模式形成四组:稳定,无低氧血症(2/20);稳定,低氧血症但改善(8/20);稳定且持续性低氧血症(5/20);不稳定,低氧血症且恶化(5/20)。多达术后第四晚仍有11例患者存在低氧血症。所有术前低氧血症患者术后均为低氧血症。术后低氧血症仅在50%的病例中得到预测。PVB组吗啡需求量减少,但区域镇痛不影响呈现每种SpO2模式的患者比例。吗啡使两个镇痛组的SpO2均降低。