Gaglia Jason L
Department of Medicine, Harvard Medical School, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.
Curr Diab Rep. 2007 Aug;7(4):309-13. doi: 10.1007/s11892-007-0050-2.
Immunologic and nonimmunologic events lead to significant graft loss after islet transplantation. Unfortunately, current metabolic testing methods are inadequate to detect many of these changes, leading to a critical need for noninvasive monitoring of islet rejection. However, their small size and distribution after transplantation pose specific problems for direct islet imaging. This article reviews the relative merits of several imaging modalities for the noninvasive monitoring of islet transplantation and rejection.
免疫和非免疫事件会导致胰岛移植后出现显著的移植物丢失。遗憾的是，目前的代谢检测方法不足以检测出其中的许多变化，这使得对胰岛排斥反应进行无创监测变得极为必要。然而，胰岛体积小且移植后分布情况特殊，给直接的胰岛成像带来了特定问题。本文综述了几种成像方式在无创监测胰岛移植和排斥反应方面的相对优势。
