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[盐酸聚六亚甲基胍(Biopag)和葡萄糖酸氯己定对颌面部和颈部化脓性炎症性疾病潜在感染病原体的抗菌作用比较分析]

[Comparative analysis of antimicrobial action of polyhexametylenguanide hydrochloride (Biopag) and chlorhexidine bigluconate upon potential infectious agent of suppurative-inflammatory diseases of maxillo-facial region and neck].

作者信息

Shipskiĭ A V, Afanas'ev V V, Polikarpov N A, Efimov K M, Dmitruk I B

出版信息

Stomatologiia (Mosk). 2007;86(3):46-50.

PMID:17690643
Abstract

Sensitivity of microflora representatives isolated from inflammatory foci from 40 patients with suppurative-inflammatory diseases of maxillo-facial region and neck to different concentrations of antiseptic preparations of polyhexametylenguanide hydrochloride (Biopag) and chlorhexidine bigluconate was tested. It was determined that 0.05-0.1% solutions of these antiseptics were optimal for these diseases treatment. Biopag had more pronounced fungicidal action, less toxic and more prolonged antimicrobial action and better organoleptic properties when compared with chlorhexidine bigluconate.

摘要

对从40例颌面部和颈部化脓性炎症疾病患者炎症病灶中分离出的微生物代表,测试其对不同浓度的盐酸聚六亚甲基胍(Biopag)和葡萄糖酸氯己定防腐剂制剂的敏感性。确定这些防腐剂的0.05 - 0.1%溶液对这些疾病的治疗是最佳的。与葡萄糖酸氯己定相比,Biopag具有更显著的杀真菌作用、更低的毒性、更长时间的抗菌作用和更好的感官特性。

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