Pal'chun V T, Lapchenko A S, Lapchenko A A, Gurov A V, Kucherov A G
Vestn Otorinolaringol. 2007(3):4-6.
Growing resistance of bacteria to wide-spectrum antibiotics gave rise to a search for new approaches to antimicrobial therapy. Photodynamic therapy (PT) was proposed for fighting against infections. It combines effects of a photosensitiser and visible light. PT produces reactive oxygen species able to kill cells. High response to PT was achieved in the treatment of local infections, in particular, in the treatment of pyoinflammatory ENT diseases caused both by gram-positive and gram-negative bacteria, fungi, especially diseases caused by bacteria with antibiotic polyresistance.
细菌对广谱抗生素的耐药性不断增强,促使人们寻找新的抗菌治疗方法。光动力疗法(PT)被提出用于对抗感染。它结合了光敏剂和可见光的作用。PT产生活性氧物质,能够杀死细胞。在局部感染的治疗中,尤其是在治疗由革兰氏阳性和革兰氏阴性细菌、真菌引起的脓性炎症性耳鼻喉疾病,特别是由具有多重抗生素耐药性的细菌引起的疾病时,PT取得了很高的疗效。