Knudsen P, Herborg H, Mortensen A R, Knudsen M, Hellebek A
Danish College of Pharmacy Practice, Milnersvej 42, DK- 3400 Hillerød, Denmark.
Qual Saf Health Care. 2007 Aug;16(4):291-6. doi: 10.1136/qshc.2006.018770.
Medication errors are a widespread problem which can, in the worst case, cause harm to patients. Errors can be corrected if documented and evaluated as a part of quality improvement. The Danish community pharmacies are committed to recording prescription corrections, dispensing errors and dispensing near misses. This study investigated the frequency and seriousness of these errors.
40 randomly selected Danish community pharmacies collected data for a defined period. The data included four types of written report of incidents, three of which already existed at the pharmacies: prescription correction, dispensing near misses and dispensing errors. Data for the fourth type of report, on adverse drug events, were collected through a web-based reporting system piloted for the project.
There were 976 cases of prescription corrections, 229 cases of near misses, 203 cases of dispensing errors and 198 cases of adverse drug events. The error rate was 23/10,000 prescriptions for prescription corrections, 1/10,000 for dispensing errors and 2/10,000 for near misses. The errors that reached the patients were pooled for separate analysis. Most of these errors, and the potentially most serious ones, occurred in the transcription stage of the dispensing process.
Prescribing errors were the most frequent type of error reported. Errors that reached the patients were not frequent, but most of them were potentially harmful, and the absolute number of medication errors was high, as provision of medicine is a frequent event in primary care in Denmark. Patient safety could be further improved by optimising the opportunity to learn from the incidents described.
用药错误是一个普遍存在的问题,在最糟糕的情况下,可能会对患者造成伤害。如果将用药错误记录下来并作为质量改进的一部分进行评估,错误是可以纠正的。丹麦社区药房致力于记录处方更正、配药错误和配药失误。本研究调查了这些错误的发生频率和严重程度。
随机选取40家丹麦社区药房,收集规定时间段内的数据。数据包括四种事件书面报告类型,其中三种在药房已经存在:处方更正、配药失误和配药错误。第四种报告类型,即药品不良事件的数据,是通过为本项目试点的基于网络的报告系统收集的。
有976例处方更正、229例失误、203例配药错误和198例药品不良事件。处方更正的错误率为每10000张处方23例,配药错误为每10000张处方1例,失误为每10000张处方2例。将发生在患者身上的错误汇总进行单独分析。这些错误中的大多数,以及潜在最严重的错误,发生在配药过程的转录阶段。
处方错误是报告中最常见的错误类型。发生在患者身上的错误并不频繁,但大多数可能有害,而且用药错误的绝对数量很高,因为在丹麦初级保健中提供药品是一项常见的工作。通过优化从所述事件中学习的机会,可以进一步提高患者安全。