季节及其他影响哮喘儿童生活质量的因素。

Seasons and other factors affecting the quality of life of asthmatic children.

作者信息

García-Marcos L, Carvajal Urueña I, Escribano Montaner A, Fernández Benítez M, García de la Rubia S, Tauler Toro E, Pérez Fernández V, Barcina Sánchez C

机构信息

Institute of Respiratory Health, University of Murcia, Murcia, Spain.

出版信息

J Investig Allergol Clin Immunol. 2007;17(4):249-56.

PMID:17694697

Abstract

OBJECTIVE

To study the effect of seasons on the health-related quality of life (HRQL) of asthmatic children.

METHODS

Four groups of asthmatic children 7 to 14 years old were recruited by pediatricians during each season of the year. Their HRQL was assessed by means of the Paediatric Asthma Quality of Life Questionnaire (PAQLQ). Other factors surveyed were asthma severity, atopy, medical treatment, immunotherapy, obesity, parental smoking, and anti-allergic measures.

RESULTS

The mean (SD) overall PAQLQ score was highest in summer at 6.2 (1.0) and lowest in autumn at 5.5 (1.2). The same trend was found for domains in summer and autumn, respectively: symptoms, 6.2 (1.0) vs 5.4 (1.4); emotions, 6.5 (0.8) vs 6.0 (1.0); and activities, 5.9 (1.4) vs. 5.0 (1.5). Factors such as male gender (odds ratio [OR], 0.60; 95% confidence interval [CI], 0.41-0.87), being on immunotherapy (OR, 0.59; 95% CI, 0.38-0.92), living in an urban environment (OR, 0.56; 0.33-0.93), and residing on the northern coast of Spain along the Bay of Biscay (OR, 0.56; 0.36-0.89) were independent protective factors against having a total PAQLQ score in the lower tertile. Conversely, being recruited in a primary care setting (OR, 1.55; 1.01-2.38) and having more severe asthma were risks for being in the lower tertile.

CONCLUSIONS

Irrespective of the severity of the disease, season has a significant influence on the HRQL of asthmatic children.

摘要

目的

研究季节对哮喘儿童健康相关生活质量（HRQL）的影响。

方法

儿科医生在一年中的每个季节招募四组7至14岁的哮喘儿童。通过儿童哮喘生活质量问卷（PAQLQ）评估他们的HRQL。调查的其他因素包括哮喘严重程度、特应性、药物治疗、免疫疗法、肥胖、父母吸烟和抗过敏措施。

结果

PAQLQ总体平均（标准差）得分在夏季最高，为6.2（1.0），在秋季最低，为5.5（1.2）。夏季和秋季各领域也发现了相同趋势：症状方面，分别为6.2（1.0）对5.4（1.4）；情绪方面，6.5（0.8）对6.0（1.0）；活动方面，5.9（1.4）对5.0（1.5）。男性（优势比[OR]，0.60；95%置信区间[CI]，0.41 - 0.87）、接受免疫疗法（OR，0.59；95%CI，0.38 - 0.92）、生活在城市环境（OR，0.56；0.33 - 0.93）以及居住在西班牙北部沿比斯开湾海岸（OR，0.56；0.36 - 0.89）等因素是防止PAQLQ总分处于较低三分位数的独立保护因素。相反，在初级保健机构招募（OR，1.55；1.01 - 2.38）以及哮喘病情更严重是处于较低三分位数的风险因素。