Pearson Wendy, Omar Semir, Clarke Andrew F
Equine Research Centre, University of Guelph, Guelph, Ontario.
Can J Vet Res. 2007 Jul;71(3):213-7.
The purpose of this study was to determine if ginseng fed at low levels enhances a horse's antibody response to vaccination against Equid herpesvirus 1 (EHV-1). For 28 d, 5 horses received ground, powdered ginseng (35 mg/kg body weight, 1.7 mg/kg total ginsenosides) in molasses as a carrier, and 5 received molasses only. On day 14, each horse was vaccinated against EHV-1. The time course of the antibody response to vaccination was significantly altered in the horses receiving ginseng, a clinically relevant increase in antibody titer being observed by postvaccination day 2 compared with day 6 in the control horses. The horses receiving ginseng also had a significant decrease in serum levels of sodium and a significant increase in serum levels of potassium. No adverse effects of ginseng treatment were identified by hematologic and blood biochemistry profiles. Thus, low-dose dietary supplementation with ginseng in healthy horses may be a useful adjunct to vaccination.
本研究的目的是确定低剂量喂食人参是否能增强马匹对1型马疱疹病毒（EHV-1）疫苗接种的抗体反应。28天里，5匹马以糖蜜为载体接受磨碎的人参粉（35毫克/千克体重，1.7毫克/千克总人参皂苷），5匹马只接受糖蜜。在第14天，每匹马接种EHV-1疫苗。接受人参的马匹对疫苗接种的抗体反应时间进程发生了显著改变，与对照马在接种后第6天相比，在接种后第2天观察到抗体滴度有临床相关的增加。接受人参的马匹血清钠水平也显著降低，血清钾水平显著升高。血液学和血液生化检查未发现人参治疗的不良反应。因此，在健康马匹中低剂量饮食补充人参可能是疫苗接种的有用辅助手段。
