Hennig Alex, Abate Joseph
Department of Orthopaedics and Rehabilitation, University of Vermont College of Medicine, Burlington, VT 05405, USA.
Sports Med Arthrosc Rev. 2007 Sep;15(3):126-32. doi: 10.1097/JSA.0b013e31812e5373.
Osteochondral allografts have demonstrated encouraging clinical and scientific success in the treatment of full-thickness articular cartilage defects in multiple anatomic locations including the knee. The use of fresh grafts has shown the greatest potential for clinical success. There has been growing interest in cryopreservation techniques and the use of cryopreserved grafts owing to the delay in obtaining grafts secondary to regulatory testing, encouraging laboratory data surrounding their use, and the potential for more effective tissue banking. This article reviews the indications, operative technique, and clinical outcomes using osteochondral allografts for full-thickness articular cartilage defects in the knee.
异体骨软骨移植在治疗包括膝关节在内的多个解剖部位的全层关节软骨缺损方面已取得了令人鼓舞的临床和科学成果。使用新鲜移植组织已显示出取得临床成功的最大潜力。由于监管测试导致获取移植组织延迟、有关其使用的实验室数据令人鼓舞以及更有效的组织库的潜力，人们对冷冻保存技术和冷冻保存移植组织的使用越来越感兴趣。本文综述了使用异体骨软骨移植治疗膝关节全层关节软骨缺损的适应症、手术技术和临床结果。
