Robertson Stuart A, Nazir Safraz, Bowker Colene, Lakhoo Kokila
Department of Paediatric Surgery, John Radcliffe Hospital, Headley Way, Oxford, UK.
Fetal Pediatr Pathol. 2007 Mar-Apr;26(2):69-73. doi: 10.1080/15513810701448326.
A previously fit and well 14-month-old-girl presented with a 2-month history of worsening cough and wheeze. Chest radiograph revealed a widened mediastinum and thoracic CT showed a large mixed density mass in the superior mediastinum, consistent with a mediastinal teratoma. Her tumor markers were within the normal range. The mass was resected and found to be a mature cystic teratoma. Surprisingly, well-formed bowel-like structures were present, containing all bowel wall layers and having a ganglionated myenteric plexus. The identification of complete sections of bowel in this context is a rare finding and to the best of our knowledge has not been published previously for the mediastinal teratoma. The possibility of secondary neoplasia developing in these areas is a complicating factor.
一名既往健康的14个月大女童,出现咳嗽和喘息加重2个月的病史。胸部X线片显示纵隔增宽,胸部CT显示上纵隔有一个大的混合密度肿块,符合纵隔畸胎瘤表现。她的肿瘤标志物在正常范围内。该肿块被切除,病理结果为成熟囊性畸胎瘤。令人惊讶的是,肿块内存在结构完整的肠样组织,包含所有肠壁层,并具有含神经节的肌间神经丛。在这种情况下发现完整的肠段是一个罕见的发现,据我们所知,此前尚未有关于纵隔畸胎瘤出现这种情况的报道。这些部位发生继发性肿瘤的可能性是一个复杂因素。