基于环糊精的聚集体及其显微镜表征

Cyclodextrin-based aggregates and characterization by microscopy.

作者信息

He Yifeng, Fu Pei, Shen Xinghai, Gao Hongcheng

机构信息

Beijing National Laboratory for Molecular Sciences (BNLMS), Department of Applied Chemistry, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.

出版信息

Micron. 2008 Jul;39(5):495-516. doi: 10.1016/j.micron.2007.06.017. Epub 2007 Jul 7.

DOI:10.1016/j.micron.2007.06.017

PMID:17706427

Abstract

Cyclodextrin-based aggregates have been widely investigated with microscopies such as STM, AFM, SEM, TEM, and fluorescent microscopy to obtain the direct morphology and structure of samples. In the present review, we discuss various types of cyclodextrin aggregates, that is, native and modified cyclodextrins, inclusion complexes and their aggregates of cyclodextrins, cyclodextrin rotaxanes and polyrotaxanes, cyclodextrin nanotubes and their secondary assembly, and other high-order aggregates of cyclodextrins. Especially, we focus on the use of microscopy to characterize above aggregates. The application of modern microscopy tools promotes the investigation on cyclodextrins.

摘要

基于环糊精的聚集体已通过扫描隧道显微镜（STM）、原子力显微镜（AFM）、扫描电子显微镜（SEM）、透射电子显微镜（TEM）和荧光显微镜等显微镜技术进行了广泛研究，以获得样品的直接形态和结构。在本综述中，我们讨论了各种类型的环糊精聚集体，即天然和改性环糊精、环糊精包合物及其聚集体、环糊精轮烷和聚轮烷、环糊精纳米管及其二级组装以及环糊精的其他高阶聚集体。特别是，我们重点介绍了使用显微镜技术来表征上述聚集体。现代显微镜工具的应用推动了对环糊精的研究。