真核生物核糖体蛋白基因的转录调控
Transcriptional regulation in eukaryotic ribosomal protein genes.
作者信息
Hu Haiyan, Li Xiaoman
机构信息
Center for Computational Biology and Bioinformatics, School of Medicine, Indiana University, 410 W. 10th Street, Indianapolis, IN 46202, USA.
出版信息
Genomics. 2007 Oct;90(4):421-3. doi: 10.1016/j.ygeno.2007.07.003. Epub 2007 Aug 17.
PMID:17707610
Abstract
Understanding ribosomal protein gene regulation provides a good avenue for understanding gene regulatory networks. Even after 5 decades of research on ribosomal protein gene regulation, little is known about how higher eukaryotic ribosomal protein genes are coordinately regulated at the transcriptional level. However, a few recent papers shed some light on this complicated problem.
摘要
了解核糖体蛋白基因调控为理解基因调控网络提供了一条很好的途径。即使经过50年对核糖体蛋白基因调控的研究，对于高等真核生物核糖体蛋白基因在转录水平上是如何协同调控的，人们仍然知之甚少。然而，最近的几篇论文为这个复杂的问题带来了一些启示。
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