Aviv Iris, Gross Zeev
Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Haifa, 32000, Israel.
Chem Commun (Camb). 2007 May 28(20):1987-99. doi: 10.1039/b618482k.
Despite of the many similarities between corroles and porphyrins, the chemistry of the former remained undeveloped for decades because of severe synthetic obstacles. The recent discoveries of facile methodologies for the synthesis of triarylcorroles and the corresponding metal complexes allowed for their utilization in various fields. This survey reveals many examples where corroles were used as the key components in catalysis, sensing of gaseous molecules and medicine-oriented research. The focus in all these cases was on the special features of corroles: stabilization of high valent transition metal ions, unique photophysical properties, large NH acidity, facile synthetic manipulation and distinct catalytic properties. The latter aspect includes several examples of reactions that are not catalyzed by any non-corrole metal complex, such as the iron-based aziridination by Chloramine-T, the clean disproportionation of peroxynitrite, and the very facile N-H activation of amines.
尽管咕啉和卟啉之间存在许多相似之处,但由于严重的合成障碍,前者的化学性质在几十年里一直未得到充分发展。最近发现了合成三芳基咕啉及其相应金属配合物的简便方法,这使得它们能够在各个领域得到应用。这项综述揭示了许多将咕啉用作催化、气态分子传感和医学导向研究的关键成分的例子。所有这些案例的重点都在于咕啉的特殊性质:高价过渡金属离子的稳定化、独特的光物理性质、较大的NH酸性、简便的合成操作以及独特的催化性质。后一个方面包括几个任何非咕啉金属配合物都无法催化的反应实例,例如氯胺-T介导的铁基氮杂环丙烷化反应、过氧亚硝酸盐的完全歧化反应以及胺类的非常容易的N-H活化反应。
Chem Commun (Camb). 2007-5-28
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