Tambyraja Andrew, Murie John, Chalmers Roderick
Edinburgh Vascular Surgical Service, Clinical & Surgical Sciences (Surgery), University of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK.
World J Surg. 2007 Nov;31(11):2243-7. doi: 10.1007/s00268-007-9181-5.
Many surgeons adopt a selective policy of intervention for a ruptured abdominal aortic aneurysm (AAA). This study aimed to develop an objective method of identifying patients suitable for attempted repair.
Consecutive patients selected for attempted repair of ruptured AAA over a 31-month period (January 2000 to July 2002) were entered into an observational study. Altogether, 53 preoperative physiological and biochemical variables were recorded and related to operative outcome.
A total of 105 patients underwent attempted repair of a ruptured AAA. There were 39 (37%) deaths in hospital or within 30 days of operation. On univariate analysis, hemoglobin <9 g/dl (p = 0.038), blood pressure <90 mmHg (p = 0.036), and Glasgow Coma Scale <15 (p = 0.016) were found to be risk factors that predicted death. Of 70 patients with no or one risk factor, 20 (29%) died. Of 30 patients with two factors, 15 (50%) died, and of the five patients with all three factors, four (80%) died. There was a significant association between mortality and cumulative risk factors (p = 0.003).
These three risk factors are easily assessed in the emergency setting and might form the basis of a scoring system to inform the outcome of ruptured AAA.
许多外科医生对破裂性腹主动脉瘤(AAA)采取选择性干预策略。本研究旨在开发一种客观方法来识别适合尝试修复的患者。
在31个月期间(2000年1月至2002年7月)选择进行破裂性AAA尝试修复的连续患者进入一项观察性研究。总共记录了53项术前生理和生化变量,并将其与手术结果相关联。
共有105例患者接受了破裂性AAA的尝试修复。39例(37%)在医院或手术后30天内死亡。单因素分析发现,血红蛋白<9 g/dl(p = 0.038)、血压<90 mmHg(p = 0.036)和格拉斯哥昏迷量表<15(p = 0.016)是预测死亡的危险因素。在70例无或有一个危险因素的患者中,20例(29%)死亡。在30例有两个危险因素的患者中,15例(50%)死亡,在5例有所有三个危险因素的患者中,4例(80%)死亡。死亡率与累积危险因素之间存在显著关联(p = 0.003)。
这三个危险因素在急诊情况下易于评估,可能构成一个评分系统的基础,以告知破裂性AAA的预后。