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腹主动脉瘤破裂后预后的预测因素:爱丁堡破裂动脉瘤评分

Predictors of outcome after abdominal aortic aneurysm rupture: Edinburgh Ruptured Aneurysm Score.

作者信息

Tambyraja Andrew, Murie John, Chalmers Roderick

机构信息

Edinburgh Vascular Surgical Service, Clinical & Surgical Sciences (Surgery), University of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK.

出版信息

World J Surg. 2007 Nov;31(11):2243-7. doi: 10.1007/s00268-007-9181-5.

Abstract

BACKGROUND

Many surgeons adopt a selective policy of intervention for a ruptured abdominal aortic aneurysm (AAA). This study aimed to develop an objective method of identifying patients suitable for attempted repair.

METHODS

Consecutive patients selected for attempted repair of ruptured AAA over a 31-month period (January 2000 to July 2002) were entered into an observational study. Altogether, 53 preoperative physiological and biochemical variables were recorded and related to operative outcome.

RESULTS

A total of 105 patients underwent attempted repair of a ruptured AAA. There were 39 (37%) deaths in hospital or within 30 days of operation. On univariate analysis, hemoglobin <9 g/dl (p = 0.038), blood pressure <90 mmHg (p = 0.036), and Glasgow Coma Scale <15 (p = 0.016) were found to be risk factors that predicted death. Of 70 patients with no or one risk factor, 20 (29%) died. Of 30 patients with two factors, 15 (50%) died, and of the five patients with all three factors, four (80%) died. There was a significant association between mortality and cumulative risk factors (p = 0.003).

CONCLUSION

These three risk factors are easily assessed in the emergency setting and might form the basis of a scoring system to inform the outcome of ruptured AAA.

摘要

背景

许多外科医生对破裂性腹主动脉瘤(AAA)采取选择性干预策略。本研究旨在开发一种客观方法来识别适合尝试修复的患者。

方法

在31个月期间(2000年1月至2002年7月)选择进行破裂性AAA尝试修复的连续患者进入一项观察性研究。总共记录了53项术前生理和生化变量,并将其与手术结果相关联。

结果

共有105例患者接受了破裂性AAA的尝试修复。39例(37%)在医院或手术后30天内死亡。单因素分析发现,血红蛋白<9 g/dl(p = 0.038)、血压<90 mmHg(p = 0.036)和格拉斯哥昏迷量表<15(p = 0.016)是预测死亡的危险因素。在70例无或有一个危险因素的患者中,20例(29%)死亡。在30例有两个危险因素的患者中,15例(50%)死亡,在5例有所有三个危险因素的患者中,4例(80%)死亡。死亡率与累积危险因素之间存在显著关联(p = 0.003)。

结论

这三个危险因素在急诊情况下易于评估,可能构成一个评分系统的基础,以告知破裂性AAA的预后。

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