Ménard O, Parache R M
Service de Pneumologie, Hôpital de Brabois, Vandoeuvre-lès-Nancy.
Ann Med Interne (Paris). 1991;142(6):423-8.
In a retrospective study of cancer patients seen between 1980 and 1990, 7 cases of metastases to skeletal muscles were found: 2 primary bronchial carcinomas, 1 spindle cell sarcoma, 1 malignant melanoma, 1 ovarian adenocarcinoma, 1 squamous cell laryngeal carcinoma and 1 malignant neuroendocrine tumor from an unknown primary site. Despite their rich blood supply, skeletal muscles are rarely secondary metastatic sites (less than 1% of all malignant metastases of hematogenous origin); only 242 cases have previously been reported in 82 publications. Primary cancers of the lung, blood, gastrointestinal tract and genitourinary tract were the most frequently involved. Although skeletal muscle metastatic sites were rarely observed, the possibility of such a colonization should be known to physicians, as their detection requires specific tests. Furthermore, the localization of such sites clearly illustrates the recent progress made in the biology of metastases, especially the organ--or tissue--specificity of the site.
在一项对1980年至1990年间诊治的癌症患者的回顾性研究中，发现了7例骨骼肌转移病例：2例原发性支气管癌、1例梭形细胞肉瘤、1例恶性黑色素瘤、1例卵巢腺癌、1例喉鳞状细胞癌以及1例原发部位不明的恶性神经内分泌肿瘤。尽管骨骼肌血供丰富，但其很少成为继发性转移部位（在所有血源性恶性转移中占比不到1%）；此前仅有82篇文献报道过242例病例。肺、血液、胃肠道和泌尿生殖道的原发性癌症是最常受累的。尽管骨骼肌转移部位很少见，但医生应了解这种转移的可能性，因为其检测需要特定的检查。此外，这些部位的定位清楚地说明了转移生物学领域最近取得的进展，尤其是转移部位的器官或组织特异性。
