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在肥厚型心肌病中,心肌切除术能带来生存获益吗?

Does myectomy convey survival benefit in hypertrophic cardiomyopathy?

作者信息

Woo Anna, Rakowski Harry

机构信息

University of Toronto, Toronto, ON, Canada.

出版信息

Heart Fail Clin. 2007 Jul;3(3):275-88. doi: 10.1016/j.hfc.2007.04.010.

Abstract

Obstructive hypertrophic cardiomyopathy (HCM) can be treated by transaortic subaortic myectomy, which has been shown to improve patients' symptoms and abolish left ventricular outflow tract obstruction. Different options, such as dual chamber pacing and septal ethanol ablation, are now available for the management of obstructive HCM, and it is important to evaluate the risks and benefits of myectomy, especially its impact on survival. In this article, the authors review the clinical course of obstructive HCM and the early and long-term results of surgery. They examine the outcomes of obstructive HCM in patients after surgical versus conservative therapy. In addition, they review the studies that have compared other techniques to surgery for the management of obstructive HCM.

摘要

梗阻性肥厚型心肌病(HCM)可通过经主动脉瓣下室间隔心肌切除术进行治疗,该手术已被证明可改善患者症状并消除左心室流出道梗阻。目前,诸如双腔起搏和室间隔乙醇消融等不同的治疗方法可用于梗阻性HCM的治疗,评估心肌切除术的风险和益处,尤其是其对生存率的影响非常重要。在本文中,作者回顾了梗阻性HCM的临床病程以及手术的早期和长期结果。他们研究了梗阻性HCM患者接受手术治疗与保守治疗后的结局。此外,他们还回顾了将其他技术与手术治疗梗阻性HCM进行比较的研究。

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