在衣原体感染率较低的女性中，比较Clearview衣原体检测法、衣原体酶免疫测定法和细胞培养法对沙眼衣原体的检测情况。
Comparison of the Clearview Chlamydia test, Chlamydiazyme, and cell culture for detection of Chlamydia trachomatis in women with a low prevalence of infection.
作者信息
Skulnick M, Small G W, Simor A E, Low D E, Khosid H, Fraser S, Chua R
机构信息
Department of Microbiology, Mount Sinai Hospital, Toronto, Ontario, Canada.
出版信息
J Clin Microbiol. 1991 Sep;29(9):2086-8. doi: 10.1128/jcm.29.9.2086-2088.1991.
Abstract
Two antigen detection systems, Clearview Chlamydia (Unipath Ltd., Bedford, United Kingdom) and Chlamydiazyme (Abbott Laboratories, North Chicago, Ill.), were compared with culture for the diagnosis of chlamydia infection in women attending gynecological clinics. Chlamydia trachomatis was isolated from 43 (4.5%) of the 965 women tested. In comparison with tissue culture, the Clearview Chlamydia and Chlamydiazyme tests had sensitivities of 79.0 and 74.4%, respectively, and both had a specificity of 99.6%. The results show that the Clearview Chlamydia test is comparable to Chlamydiazyme for the detection of C. trachomatis from endocervical specimens in a population with a low prevalence of infection.
摘要
比较了两种抗原检测系统Clearview衣原体检测试剂盒（英国贝德福德Unipath有限公司）和衣原体酶免疫检测试剂盒（美国伊利诺伊州北芝加哥雅培实验室）与培养法在诊断妇科门诊就诊女性衣原体感染中的应用。在接受检测的965名女性中，有43名（4.5%）分离出沙眼衣原体。与组织培养相比，Clearview衣原体检测试剂盒和衣原体酶免疫检测试剂盒的敏感性分别为79.0%和74.4%，两者的特异性均为99.6%。结果表明，在感染率较低的人群中，从宫颈标本中检测沙眼衣原体时，Clearview衣原体检测试剂盒与衣原体酶免疫检测试剂盒相当。
相似文献
1
Comparison of the Clearview Chlamydia test, Chlamydiazyme, and cell culture for detection of Chlamydia trachomatis in women with a low prevalence of infection.在衣原体感染率较低的女性中，比较Clearview衣原体检测法、衣原体酶免疫测定法和细胞培养法对沙眼衣原体的检测情况。
J Clin Microbiol. 1991 Sep;29(9):2086-8. doi: 10.1128/jcm.29.9.2086-2088.1991.
2
Use of chlamydiazyme for the detection of Chlamydia trachomatis in genital infections.使用衣原体酶免疫诊断试剂盒检测生殖器感染中的沙眼衣原体。
Microbiologica. 1987 Oct;10(4):421-5.
3
Evaluation of a novel solid-phase immunoassay, Clearview Chlamydia, for the rapid detection of Chlamydia trachomatis.评估一种新型固相免疫测定法Clearview衣原体检测试剂盒用于快速检测沙眼衣原体。
J Clin Microbiol. 1990 Dec;28(12):2813-4. doi: 10.1128/jcm.28.12.2813-2814.1990.
4
Enzyme immunoassay for detection of Chlamydia trachomatis from the cervix.用于检测宫颈沙眼衣原体的酶免疫测定法。
Obstet Gynecol. 1985 Apr;65(4):523-6.
5
A comparison of an enzyme immunoassay and cell culture for detection of Chlamydia trachomatis in genito-urinary specimens.
Sex Transm Dis. 1988 Apr-Jun;15(2):123-6. doi: 10.1097/00007435-198804000-00013.
6
Diagnosis of Chlamydia trachomatis genital infections by cell culture and two enzyme immunoassays detecting different chlamydial antigens.
J Clin Microbiol. 1989 Sep;27(9):1934-8. doi: 10.1128/jcm.27.9.1934-1938.1989.
7
TestPack Chlamydia, a new rapid assay for the direct detection of Chlamydia trachomatis.衣原体检测试剂盒，一种用于直接检测沙眼衣原体的新型快速检测方法。
J Clin Microbiol. 1989 Dec;27(12):2811-4. doi: 10.1128/jcm.27.12.2811-2814.1989.
8
A comparison of three rapid chlamydial tests in pregnant and nonpregnant women.孕妇和非孕妇中三种衣原体快速检测方法的比较。
J Fam Pract. 1992 May;34(5):593-7.
9
[Sensitivity and specificity of the Chlamydiazyme test in comparison with tissue culture in the light of our studies].[根据我们的研究，衣原体酶试验与组织培养相比的敏感性和特异性]
Przegl Dermatol. 1990 Mar-Apr;77(2):122-7.
10
[Detection of Chlamydia trachomatis antigen with an enzyme immunoassay].[用酶免疫测定法检测沙眼衣原体抗原]
Hautarzt. 1986 Jan;37(1):37-41.
引用本文的文献
1
Point of care diagnostics for sexually transmitted infections: perspectives and advances.性传播感染的即时诊断：观点与进展
Expert Rev Anti Infect Ther. 2014 Jun;12(6):657-72. doi: 10.1586/14787210.2014.880651. Epub 2014 Feb 3.
2
A multiplexed microfluidic PCR assay for sensitive and specific point-of-care detection of Chlamydia trachomatis.一种多重微流控 PCR 检测法，用于敏感且特异地即时检测沙眼衣原体。
PLoS One. 2012;7(12):e51685. doi: 10.1371/journal.pone.0051685. Epub 2012 Dec 14.
3
What's the Point? How Point-of-Care STI Tests Can Impact Infected Patients.要点何在？即时性性传播感染检测如何影响感染患者。
Point Care. 2010 Mar 1;9(1):36-46. doi: 10.1097/POC.0b013e3181d2d8cc.
4
Clinic-based evaluation of Clearview Chlamydia MF for detection of Chlamydia trachomatis in vaginal and cervical specimens from women at high risk in China.基于临床的Clearview衣原体MF检测法在中国高危女性阴道和宫颈标本中检测沙眼衣原体的评估
Sex Transm Infect. 2006 Dec;82 Suppl 5(Suppl 5):v33-7. doi: 10.1136/sti.2006.022475. Epub 2006 Nov 22.
5
Impact of reference standard sensitivity on accuracy of rapid antigen detection assays and a leukocyte esterase dipstick for diagnosis of Chlamydia trachomatis infection in first-void urine specimens from men.参考标准敏感性对快速抗原检测试验及白细胞酯酶试纸条检测男性首次晨尿标本中沙眼衣原体感染准确性的影响
J Clin Microbiol. 1999 Sep;37(9):2777-80. doi: 10.1128/JCM.37.9.2777-2780.1999.
6
Comparison of the PACE 2 assay, two amplification assays, and Clearview EIA for detection of Chlamydia trachomatis in female endocervical and urine specimens.PACE 2检测法、两种扩增检测法及Clearview酶免疫测定法用于检测女性宫颈内膜和尿液标本中沙眼衣原体的比较
J Clin Microbiol. 1999 Jul;37(7):2223-9. doi: 10.1128/JCM.37.7.2223-2229.1999.
7
Head-to-head evaluation of five chlamydia tests relative to a quality-assured culture standard.将五种衣原体检测方法与质量保证的培养标准进行直接比较评估。
J Clin Microbiol. 1999 Mar;37(3):681-5. doi: 10.1128/JCM.37.3.681-685.1999.
8
Comparison of the Clearview Chlamydia, the PACE 2 assay, and culture for detection of Chlamydia trachomatis from cervical specimens in a low-prevalence population.在低流行率人群中，比较Clearview衣原体检测法、PACE 2检测法和培养法用于检测宫颈标本中沙眼衣原体的效果。
J Clin Microbiol. 1993 Jun;31(6):1622-5. doi: 10.1128/jcm.31.6.1622-1625.1993.
9
Evaluation of Clearview and Magic Lite tests, polymerase chain reaction, and cell culture for detection of Chlamydia trachomatis in urogenital specimens.评估Clearview和Magic Lite检测、聚合酶链反应及细胞培养法在泌尿生殖系统标本中检测沙眼衣原体的效果。
J Clin Microbiol. 1993 Dec;31(12):3204-10. doi: 10.1128/jcm.31.12.3204-3210.1993.
10
Clinical evaluation of a new polymerase chain reaction assay for detection of Chlamydia trachomatis in endocervical specimens.一种用于检测宫颈标本中沙眼衣原体的新型聚合酶链反应检测方法的临床评估
J Clin Microbiol. 1993 Oct;31(10):2648-53. doi: 10.1128/jcm.31.10.2648-2653.1993.
本文引用的文献
1
Epidemiology of sexually transmitted Chlamydia trachomatis infections.性传播沙眼衣原体感染的流行病学
Epidemiol Rev. 1983;5:96-123. doi: 10.1093/oxfordjournals.epirev.a036266.
2
Diagnosis of chlamydial infection in women attending antenatal and gynecologic clinics.对产前和妇科门诊就诊女性衣原体感染的诊断。
J Clin Microbiol. 1987 May;25(5):868-72. doi: 10.1128/jcm.25.5.868-872.1987.
3
Comparison of three techniques for detection of Chlamydia trachomatis in endocervical specimens from asymptomatic women.三种检测无症状女性宫颈标本中沙眼衣原体方法的比较。
J Clin Microbiol. 1988 Apr;26(4):726-31. doi: 10.1128/jcm.26.4.726-731.1988.
4
Centers for Disease Control guidelines for prevention and control of Chlamydia trachomatis infections. Summary and Commentary.疾病控制中心沙眼衣原体感染预防与控制指南。总结与评论。
Ann Intern Med. 1986 Apr;104(4):524-6. doi: 10.7326/0003-4819-104-4-524.
5
Effect of differences in specimen processing and passage technique on recovery of Chlamydia trachomatis.标本处理和传代技术差异对沙眼衣原体回收的影响。
J Clin Microbiol. 1989 May;27(5):894-8. doi: 10.1128/jcm.27.5.894-898.1989.
6
Diagnosis of Chlamydia trachomatis genital infections by cell culture and two enzyme immunoassays detecting different chlamydial antigens.
J Clin Microbiol. 1989 Sep;27(9):1934-8. doi: 10.1128/jcm.27.9.1934-1938.1989.
7
Cytobrush in collection of cervical specimens for detection of Chlamydia trachomatis.用于检测沙眼衣原体的宫颈标本采集的细胞刷
J Clin Microbiol. 1989 Aug;27(8):1863-6. doi: 10.1128/jcm.27.8.1863-1866.1989.
8
Comparison of DNA probe, monoclonal antibody enzyme immunoassay, and cell culture for the detection of Chlamydia trachomatis.用于检测沙眼衣原体的DNA探针、单克隆抗体酶免疫测定法和细胞培养法的比较
J Clin Microbiol. 1989 May;27(5):826-8. doi: 10.1128/jcm.27.5.826-828.1989.
9
Quantitative culture of endocervical Chlamydia trachomatis.宫颈沙眼衣原体定量培养
J Clin Microbiol. 1990 Apr;28(4):774-80. doi: 10.1128/jcm.28.4.774-780.1990.
10
Evaluation of a novel solid-phase immunoassay, Clearview Chlamydia, for the rapid detection of Chlamydia trachomatis.评估一种新型固相免疫测定法Clearview衣原体检测试剂盒用于快速检测沙眼衣原体。
J Clin Microbiol. 1990 Dec;28(12):2813-4. doi: 10.1128/jcm.28.12.2813-2814.1990.
Zotero 插件