Science. 1978 Jun 9;200(4346):1151-3. doi: 10.1126/science.200.4346.1151.
Heavy charged particle beams can be widely used for cancer therapy if control in heterogeneous tissue is proved practical. A beam of protons at 200 million electron volts has been visualized in plastic and in a living animal by using an on-line positron camera. The fraction of the activity retained in the radiation site was found to be at least 70 percent of that produced in a dead animal. The sensitivity of the technique was established for a typical geometry.
如果在不均匀组织中实现控制成为现实,重荷电粒子束可广泛用于癌症治疗。通过使用在线正电子照相机,已在塑料和活体动物中观察到 2 亿电子伏的质子束。发现在辐射部位保留的放射性活度至少为在死动物中产生的放射性活度的 70%。对于典型的几何形状,已经确定了该技术的灵敏度。