Scholten Paul, Sheikh Mateen, Atchison James, Eldrige Jason S, Garcia Diogo, Sandhu Sukhwinder, Qu Wenchun, Nottmeier Eric, Fox W Christopher, Buchanan Ian, Pirris Stephen, Chen Selby, Quinones-Hinojosa Alfredo, Abode-Iyamah Kingsley
Department of Physical Medicine & Rehabilitation, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
University of North Florida, 1 UNF Dr., Jacksonville, FL, 32224, USA.
Interv Pain Med. 2024 Jan 23;3(1):100387. doi: 10.1016/j.inpm.2024.100387. eCollection 2024 Mar.
Lumbar facet arthritis is a significant source of back pain and impaired function that is amenable to treatment with medial branch radiofrequency neurotomy (RFN). Identifying appropriate patients for this treatment requires integration of information from the history, physical exam, and diagnostic imaging, but the current diagnostic standard for facet-mediated pain is positive comparative medial branch blocks (MBBs). Lumbar SPECT-CT has recently been evaluated as a potential predictor of positive MBBs with mixed results. The purpose of this retrospective analysis was to determine if the level of concordance between SPECT-CT uptake and facet joints targeted with MBB was associated with a positive block.
A retrospective review was performed to identify all patients undergoing lumbar MBB within 12 months after having a lumbar SPECT-CT. Each procedure was classified into one of four categories based on the level of concordance between facet joints demonstrating increased Tc uptake on SPECT-CT and those being blocked: 1) Complete Concordance (all joints demonstrating increased uptake were blocked and no additional joints blocked); 2) Partial Concordance (all joints demonstrating increased uptake were blocked, with at least one joint not demonstrating increased uptake blocked); 3) Partial Discordance (at least one but not all joints demonstrating increased uptake were blocked); 4) Complete Discordance (all blocks performed at joints not demonstrating increased uptake). Statistical analysis was performed to determine if the level of concordance between increased uptake on SPECT-CT and joints undergoing MBB was associated with a positive block using cutoffs of 50 % and 80 % pain relief.
A total of 180 procedures were analyzed (23 % Complete Concordance, 22 % Partial Concordance, 31 % Partial Discordance, 24 % Complete Discordance) and all groups demonstrated improvement in pain Numeric Rating Scale (NRS) scores. There was no significant association between level of concordance and having a positive block using thresholds of 50 % pain relief, (3, = 180) = 4.880, p = .181; or 80 % pain relief, (3, = 180) = 1.272, p = .736.
SPECT-CT findings do not accurately predict positive lumbar MBB but may provide valuable information that can be considered with other factors when deciding which joints to treat.
腰椎小关节关节炎是背痛和功能受损的重要原因,可通过内侧支射频神经切断术(RFN)进行治疗。确定适合该治疗的患者需要整合病史、体格检查和诊断成像的信息,但目前小关节介导性疼痛的诊断标准是对比性内侧支阻滞(MBB)结果为阳性。腰椎单光子发射计算机断层扫描-计算机断层扫描(SPECT-CT)最近被评估为MBB阳性的潜在预测指标,结果不一。本回顾性分析的目的是确定SPECT-CT摄取与MBB靶向的小关节之间的一致性水平是否与阻滞阳性相关。
进行回顾性研究,以确定在接受腰椎SPECT-CT后12个月内接受腰椎MBB的所有患者。根据SPECT-CT上显示锝摄取增加的小关节与被阻滞的小关节之间的一致性水平,将每个手术分为四类之一:1)完全一致(所有显示摄取增加的关节均被阻滞,且无其他关节被阻滞);2)部分一致(所有显示摄取增加的关节均被阻滞,至少有一个未显示摄取增加的关节被阻滞);3)部分不一致(至少有一个但并非所有显示摄取增加的关节被阻滞);4)完全不一致(所有阻滞均在未显示摄取增加的关节进行)。进行统计分析,以确定SPECT-CT上摄取增加与接受MBB的关节之间的一致性水平是否与使用50%和80%疼痛缓解阈值的阻滞阳性相关。
共分析了180例手术(23%完全一致,22%部分一致,31%部分不一致,24%完全不一致),所有组的疼痛数字评分量表(NRS)得分均有改善。使用50%疼痛缓解阈值时,一致性水平与阻滞阳性之间无显著相关性,(3,=180)=4.880,p=0.181;或使用80%疼痛缓解阈值时,(3,=180)=1.272,p=0.736。
SPECT-CT检查结果不能准确预测腰椎MBB阳性,但可能提供有价值的信息,在决定治疗哪些关节时可与其他因素一起考虑。