• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

鹰嘴豆的降血脂原理：生物活性成分染料木黄酮和芒柄花黄素。

Hypolipidemic principles of Cicer arietinum: biochanin-A and formononetin.

作者信息

Siddiqui M T, Siddiqi M

出版信息

Lipids. 1976 Mar;11(3):243-6. doi: 10.1007/BF02532865.

DOI:10.1007/BF02532865
PMID:177835
Abstract

Two isoflavones, biochanin-A and formononetin isolated from gram Cicer arietinum, have been shown to possess hypolipidemic properties for Triton WR-1339 induced hyperlipidemia in male albino rats, when administered as a crude extract or as individual compounds.

摘要

从鹰嘴豆中分离出的两种异黄酮，即鹰嘴豆芽素A和芒柄花黄素，当以粗提物或单独化合物形式给药时，已显示出对雄性白化病大鼠由Triton WR - 1339诱导的高脂血症具有降血脂特性。

相似文献

1
Hypolipidemic principles of Cicer arietinum: biochanin-A and formononetin.鹰嘴豆的降血脂原理：生物活性成分染料木黄酮和芒柄花黄素。
Lipids. 1976 Mar;11(3):243-6. doi: 10.1007/BF02532865.
2
Effect of various isoflavones on lipid levels in triton-treated rats.不同异黄酮对 Triton 处理的大鼠血脂水平的影响。
Atherosclerosis. 1979 Jul;33(3):371-5. doi: 10.1016/0021-9150(79)90189-8.
3
Isoflavones and hypercholesterolemia in rats.
Lipids. 1979 Jun;14(6):535-9. doi: 10.1007/BF02533528.
4
Antihypercholesterolemic and antioxidative effects of an extract of the oyster mushroom, Pleurotus ostreatus, and its major constituent, chrysin, in Triton WR-1339-induced hypercholesterolemic rats.牡蛎蘑菇（Pleurotus ostreatus）提取物及其主要成分白杨素对 Triton WR-1339 诱导的高胆固醇血症大鼠的降胆固醇和抗氧化作用。
J Physiol Biochem. 2013 Jun;69(2):313-23. doi: 10.1007/s13105-012-0215-6. Epub 2012 Oct 27.
5
Reduced LDL- and increased HDL-apoproteins in patients with hypercholesterolaemia under treatment with bezafibrate.接受苯扎贝特治疗的高胆固醇血症患者低密度脂蛋白降低，高密度脂蛋白载脂蛋白升高。
Atherosclerosis. 1981 Oct;40(2):153-8. doi: 10.1016/0021-9150(81)90033-2.
6
[Low-density lipoprotein cholesterol levels in hypercholesterolemic rabbits with or without carbon monoxide poisoning].
Ann Nutr Metab. 1984;28(2):117-22. doi: 10.1159/000176791.
7
Effect of garlic (Allium sativum linn) on serum lipoproteins and lipoprotein cholesterol levels in albino rats rendered hypercholesteremic by feeding cholesterol.大蒜（葱属植物大蒜）对通过喂食胆固醇而致高胆固醇血症的白化大鼠血清脂蛋白和脂蛋白胆固醇水平的影响。
Lipids. 1982 Jul;17(7):483-8. doi: 10.1007/BF02535329.
8
Hypolipidemic effect of triphala in experimentally induced hypercholesteremic rats.三果木对实验性诱导的高胆固醇血症大鼠的降血脂作用。
Yakugaku Zasshi. 2007 Feb;127(2):385-8. doi: 10.1248/yakushi.127.385.
9
Assessment of Antihyperlipidemic and Antitumor Effect of Isolated Active Phytoconstituents from Apium graveolens L. through Bioassay-Guided Procedures.通过生物测定指导程序评估芹菜中分离出的活性植物成分的降血脂和抗肿瘤作用。
J Diet Suppl. 2019;16(2):193-206. doi: 10.1080/19390211.2018.1448921. Epub 2018 Apr 6.
10
Serum lipid and lipoprotein fractions in bengal gram and biochanin A induced alterations in atherosclerosis.鹰嘴豆和鹰嘴豆芽素A诱导的动脉粥样硬化改变中的血清脂质和脂蛋白组分
Indian Heart J. 1991 May-Jun;43(3):185-9.

引用本文的文献

1
Biochanin A abrogates osteoclastogenesis in type 2 diabetic osteoporosis via regulating ROS/MAPK signaling pathway based on integrating molecular docking and experimental validation.染料木黄酮 A 通过调控 ROS/MAPK 信号通路抑制 2 型糖尿病骨质疏松症破骨细胞分化：基于分子对接和实验验证的整合分析。
BMC Complement Med Ther. 2024 Jan 8;24(1):24. doi: 10.1186/s12906-023-04332-x.
2
A Study of the Mechanisms and Characteristics of Fluorescence Enhancement for the Detection of Formononetin and Ononin.大豆苷元和芒柄花素的荧光增强检测的机制和特性研究。
Molecules. 2023 Feb 5;28(4):1543. doi: 10.3390/molecules28041543.
3
L.: A Rich Source of Flavonoids with Anti-inflammatory Activity.

本文引用的文献

1
EFFECT OF BENGAL GRAM ON EXPERIMENTALLY INDUCED HIGH LEVELS OF CHOLESTEROL IN TISSUES AND SERUM IN ALBINO RATS.孟加拉鹰嘴豆对实验诱导的白化大鼠组织和血清中高胆固醇水平的影响。
J Nutr. 1964 Nov;84:201-4. doi: 10.1093/jn/84.3.201.
2
Comparative tests for rapid evaluation of hypocholesteremic compounds.用于快速评估降胆固醇化合物的对比试验。
Arzneimittelforschung. 1959 Apr;9(4):206-7.
3
Micromethod for the direct determination of serum triglycerides.直接测定血清甘油三酯的微量法。
L.：一种具有抗炎活性的黄酮类化合物的丰富来源。
Medicines (Basel). 2020 May 30;7(6):31. doi: 10.3390/medicines7060031.
4
Biochanin A attenuates myocardial ischemia/reperfusion injury through the TLR4/NF-κB/NLRP3 signaling pathway.大豆黄素通过TLR4/NF-κB/NLRP3信号通路减轻心肌缺血/再灌注损伤。
Acta Cir Bras. 2019 Dec 20;34(11):e201901104. doi: 10.1590/s0102-865020190110000004. eCollection 2019.
5
Anxiolytic effects of Formononetin in an inflammatory pain mouse model.芒柄花素在炎症性疼痛小鼠模型中的抗焦虑作用。
Mol Brain. 2019 Apr 8;12(1):36. doi: 10.1186/s13041-019-0453-4.
6
Antihyperlipidemic activity of chickpea sprouts supplementation in ovariectomy-induced dyslipidemia in rats.鹰嘴豆芽补充剂对大鼠卵巢切除诱导的血脂异常的抗高血脂活性。
J Ayurveda Integr Med. 2015 Apr-Jun;6(2):104-10. doi: 10.4103/0975-9476.146546.
7
Isoflavones and hypercholesterolemia in rats.
Lipids. 1979 Jun;14(6):535-9. doi: 10.1007/BF02533528.
J Lab Clin Med. 1957 Jul;50(1):152-7.
4
A simple method for the isolation and purification of total lipides from animal tissues.一种从动物组织中分离和纯化总脂质的简单方法。
J Biol Chem. 1957 May;226(1):497-509.
5
A new method for the direct determination of serum cholesterol.一种直接测定血清胆固醇的新方法。
J Lab Clin Med. 1953 Mar;41(3):486-92.
6
Effect of Bengal gram, Kabuli gram, green gram and Bajra on serum and tissue lipids in rabbits fed on hypercholesterolaemic diet.孟加拉鹰嘴豆、卡布利鹰嘴豆、绿豆和珍珠粟对高胆固醇饮食喂养的家兔血清和组织脂质的影响。
J Assoc Physicians India. 1965 Dec;13(12):923-8.
7
Hypocholesterolaemic effect of Bengal gram: a long-term study in man.鹰嘴豆的降胆固醇作用：一项对人体的长期研究。
Br Med J. 1968 Jan 6;1(5583):30-1. doi: 10.1136/bmj.1.5583.30.
8
Effects of certain Indian pulses on the serum, liver and aortic lipid levels in rats fed a hypercholesterolaemic diet.某些印度豆类对喂食高胆固醇饮食大鼠的血清、肝脏和主动脉脂质水平的影响。
Atherosclerosis. 1970 May-Jun;11(3):479-84. doi: 10.1016/0021-9150(70)90026-2.
9
Anti-hypercholesterolemic effect of a sulfur containing amino acid, S-methyl-L-cysteine sulfoxide, isolated from cabbage.从卷心菜中分离出的含硫氨基酸S-甲基-L-半胱氨酸亚砜的抗高胆固醇血症作用
Experientia. 1972 Mar 15;28(3):254-5. doi: 10.1007/BF01928671.
10
Triton-induced hyperlipidemia in rats as an animal model for screening hypolipidemic drugs.以 Triton 诱导的大鼠高脂血症作为筛选降血脂药物的动物模型。
Lipids. 1972 Jan;7(1):68-74. doi: 10.1007/BF02531272.