Niilo L
Res Vet Sci. 1976 Mar;20(2):225-6.
Lethal doses of enterotoxin of Clostridium welchii (perfringens) type A injected intravenously into young fowls caused immediate lassitude, with partial recovery, followed by death seven to 35 h after inoculation. Lesions found were ascites, hydropericardium, oedema of the muscles, hepatic congestion, urate deposits on the peritoneum and the pericardium, and intestinal hyperaemia. Sublethal doses produced no clinical signs or lesion. The LD50 of this enterotoxin was 74-84 mug/kg of body weight.
将A型魏氏梭菌（产气荚膜梭菌）肠毒素的致死剂量静脉注射到幼禽体内，会使其立即出现倦怠，部分恢复后，在接种后7至35小时死亡。发现的病变有腹水、心包积水、肌肉水肿、肝脏充血、腹膜和心包上有尿酸盐沉积以及肠道充血。亚致死剂量未产生临床症状或病变。这种肠毒素的半数致死剂量为74 - 84微克/千克体重。
